The aged tumor microenvironment limits T cell control of cancer

已完结 10 由丫丫发布于 2024/7/5 10:05:46

DOI:10.1038/s41590-024-01828-7
作者：Alex C. Y. Chen, Sneha Jaiswal, Daniela Martinez, Cansu Yerinde, Keely Ji, Velita Miranda, Megan E. Fung, Sarah A. Weiss, Maria Zschummel, Kazuhiro Taguchi, Christopher S. Garris, Thorsten R. Mempel, Nir Hacohen, Debattama R. Sen
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：The etiology and effect of age-related immune dysfunction in cancer is not completely understood. Here we show that limited priming of CD8+ T cells in the aged tumor microenvironment (TME) o

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