Tailored Monoacyl Poly(2-oxazoline)- and Poly(2-oxazine)-Lipids as PEG-Lipid Alternatives for Stabilization and Delivery of mRNA-Lipid Nanoparticles

已完结 10 由 1236544 发布于 2024/7/22 9:05:41

DOI:10.1021/acs.biomac.4c00651
作者：Xie He, Thomas J. Payne, Asuka Takanashi, Yunji Fang, Simran D. Kerai, Joshua P. Morrow, Hareth Al-Wassiti, Colin W. Pouton* and Kristian Kempe*,
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：The successful use of lipid nanoparticles (LNPs) for clinical development of the COVID-19 mRNA vaccines marked a breakthrough in mRNA-LNP therapeutics. As one of the vital components of LNPs

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