Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency.

已完结 10 由 1236544 发布于 2024/7/16 21:46:29

DOI:10.1016/j.ymthe.2024.06.021
作者：Philip M Zakas, Sharon C Cunningham, Ann Doherty, Eva B van Dijk, Raed Ibraheim, Stephanie Yu, Befikadu D Mekonnen, Brendan Lang, Elizabeth J English, Gang Sun, Miles C Duncan, Matthew S Benczkowski, Robert C Altshuler, Malvenderjit Jagjit Singh, Emily S Kibbler, Gulen Y Tonga, Zi Jun Wang, Z Jane Wang, Guangde Li, Ding An, James B Rottman, Yashvi Bhavsar, Cormac Purcell, Rachit Jain, Ryan Alberry, Nathaniel Roquet, Yanfang Fu, Robert J Citorik, Jacob R Rubens, Michael C Holmes, Cecilia Cotta-Ramusino, William Querbes, Ian E Alexander, William E Salomon
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Recombinant adeno-associated virus (rAAV) vector gene delivery systems have demonstrated great promise in clinical trials but continue to face durability and dose-related challenges. Unlike

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:其它数据库基于绩效的水环境治理PPP项目激励机制研究