Robust and Scalable Reductive Amination Protocol for Electron-Poor Heterocyclic Amines Using Et 3 SiH/TFA as Reducing Agent

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DOI:10.1055/a-1981-2727
作者：G. Schäfer, S. Reber, Muhamed Ahmetovic, Tony Fleischer, Daniel Leuenberger, Nicole Blumer, M. Udry, Stefan Abele
文献类型：期刊论文
补充材料：只需要正文

Thieme Medical Publishers

Abstract：A novel reductive amination procedure for electron-poor heterocyclic amines with aromatic and aliphatic aldehydes has been developed. The key to success was the use of triethylsilane (Et3SiH

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