Characterization of a Potential KOR/DOR Dual Agonist with No Apparent Abuse Liability via a Complementary Structure–Activity Relationship Study on Nalfurafine Analogues

已完结 10 由何尘发布于 2024/5/6 16:43:54

DOI:10.1021/acschemneuro.2c00526
作者：Mengchu Li, David L. Stevens, Michelle Arriaga, E. Andrew Townsend, Rolando E. Mendez, Nadejda A. Blajkevch, Dana E. Selley, Matthew L. Banks, S. Stevens Negus, William L. Dewey and Yan Zhang*,
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Discovery of analgesics void of abuse liability is critical to battle the opioid crisis in the United States. Among many strategies to achieve this goal, targeting more than one opioid recep

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