Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors

已完结 10 由小太阳发布于 2024/5/17 18:14:40

DOI:10.1021/acs.jmedchem.2c01143
作者：Rongjun He, Jifeng Wang, Zhi-Hong Yu, Julie S. Moyers, M. Dodson Michael, Timothy B. Durham, Jeff W. Cramer, Yuewei Qian, Amy Lin, Li Wu, Nicholas Noinaj, David G. Barrett* and Zhong-Yin Zhang*,
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Protein tyrosine phosphatases constitute an important class of drug targets whose potential has been limited by the paucity of drug-like small-molecule inhibitors. We recently described a cl

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:ElsevierJiangu granules ameliorate postmenopausal osteoporosis via rectifying bone homeostasis imbalance: A network pharmacology analysis based on multi-omics validation