Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry

已完结 10 由 1236544 发布于 2024/5/15 22:14:41

DOI:10.1038/s41563-024-01867-3
作者：Bowen Li, Idris O. Raji, Akiva G. R. Gordon, Lizhuang Sun, Theresa M. Raimondo, Favour A. Oladimeji, Allen Y. Jiang, Andrew Varley, Robert S. Langer, Daniel G. Anderson
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：To unlock the full promise of messenger (mRNA) therapies, expanding the toolkit of lipid nanoparticles is paramount. However, a pivotal component of lipid nanoparticle development that remai

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