Ketoreductase-Mediated Stereodivergent Synthesis of 1,1-Disubstituted Cyclobutan-3-ols

已完结 10 由小太阳发布于 2024/5/22 14:16:15

DOI:10.1021/acs.oprd.4c00126
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Selective access to both cis- and trans-isomers of α-substituted 3-hydroxycyclobutane-1-carboxylic esters has been demonstrated using ketoreductase (KRED) enzymes. Two stereocomplementary KR

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