Conformation-Transformable, Spiked Polypeptide Enables In Situ Cancer Vaccination via Conditional Antigen Capture and STING Activation

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DOI:10.1021/jacs.5c22249
作者：Chenglong Ge,?, ,?Fan Wu,?, ,?Xinke Zhang,?, ,?Mengyuan Yin,?, ,?Jianyin He,?, ,?Jing Yan,?, ,?Yu Qian,?, ,?Huan Ye,?, ,?Kai Yang*,?, and ,?Lichen Yin*,?
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Abstract：Cancer vaccines based on autologous tumor antigens hold profound promise for antitumor immunotherapy but are challenged by the low efficiency and lack of cancer-selectivity in terms of antig

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