Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A⁺ myeloid cells to promote liver cancer progression.

已完结 10 由顺顺利利毕业发布于 2026/5/6 15:57:25

DOI:10.1136/gutjnl-2024-332429
作者：Yang Yang,?Tianduo Pei,?Chaobao Liu,?Mingtao Cao,?Xiaolin Hu,?Jie Yuan,?Fengqian Chen,?Bao Guo,?Yuemei Hong,?Jibin Liu,?Bin Li,?Xiaoguang Li,?Hui Wang
文献类型：期刊论文
补充材料：只需要正文

BMJ

Abstract：Objective: The metabolic characteristics of liver cancer drive considerable hurdles to immune cells function and cancer immunotherapy. However, how metabolic reprograming in the tumour micro

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Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A+ myeloid cells to promote liver cancer progression.

Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A⁺ myeloid cells to promote liver cancer progression.