JOSD1 drives hepatocellular carcinoma malignancy by modulating the ubiquitination-lactylation switch on PGAM1.

已完结 10 由华山令狐冲发布于 2026/5/6 9:08:34

DOI:10.1136/gutjnl-2025-337331
作者：Qing Li,Kai Yu,Suiqing Zhou,Chunyao Fang,Liren Zhang,Feiyu Jin,Xiangyu Hou,Feifan Yao,Yuhong Tang,Jiali Xu,Ruizhi Zhang,Hao Peng,Song Tian,Yang Hu,Dianyu Liu,Xiaofeng Tie,Xiaoyu Liu,Shu Chen,Guandou Y
文献类型：期刊论文
补充材料：只需要正文

BMJ

Abstract：BACKGROUND Metabolic reprogramming is a hallmark of hepatocellular carcinoma (HCC), enabling rapid tumour growth and immune evasion. Protein post-translational modification (PTM) crosstalk

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