Novel selective morpholine trace amine-associated receptor 1 partial agonists show promising preclinical effects for neuropsychiatric disorders and are well tolerated in healthy volunteers

已完结 10 由未冰BBw 发布于 2026/4/12 15:10:45

DOI:10.1038/s41380-026-03465-y
作者：Céline Fournier, Danièle Buchy, Susanne Mohr, Axel P?hler, Bjoern Jacobsen, Roger Norcross, Philippe Pflieger, Sabine Sewing, Andrea Greiter-Wilke, Basil Kuennecke, Christophe Schmitt, Mary Morrison
文献类型：期刊论文
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Springer

Abstract：Trace amine-associated receptor 1 (TAAR1) is a novel target for antipsychotic and potentially mood-stabilizing and anti-addictive drugs, offering a new mechanism by modulating dopaminergic,

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