Synthetic SIGLEC9-based chimeric switch receptor augments the efficacy of CAR macrophages against glioblastoma

已完结 20 由 sailor 发布于 2026/4/13 16:12:48

DOI:10.1073/pnas.2519819123
作者：Zhipeng Fu, Xiaotian Zhao, Qikang Zhang, Maosen Han, Jing Zhang, Zhenmei Yang, Yan Wang, Zichao Yao, Ying Liu, Chunwei Tang, Kaiyan Xi, Zhanyan Liu, Yi Zhang, Kun Zhao, Na Li, Yulin Zhang, Yudong Song
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1073/pnas.2519819123

Proceedings of the National Academy of Sciences of the United States of America (PNAS)

Abstract：Chimeric antigen receptor macrophage (CAR-M) therapy represents a promising therapeutic approach for treating glioblastoma multiforme (GBM). However, durable antitumorigenic macrophage pheno

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