阻断传播:流感病毒传播的障碍。

IF 8.1 1区 医学 Q1 VIROLOGY
Annual Review of Virology Pub Date : 2023-09-29 Epub Date: 2023-06-12 DOI:10.1146/annurev-virology-111821-115447
Valerie Le Sage, Anice C Lowen, Seema S Lakdawala
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引用次数: 0

摘要

呼吸道病毒,如流感病毒,通过季节性流行病和散发性流行病在全球范围内造成严重的发病率和死亡率。流感病毒通过多种方式传播,包括接触(直接或通过受污染的表面)和吸入排出的气溶胶。成功的人传人需要将病毒排出环境的受感染供体、易感受体以及排出的病毒在环境中的持久性。每种模式的相对效率可以通过病毒特征、环境参数、供体和受体宿主特征以及病毒持久性来改变。减少流感病毒传播的干预措施可以针对这些因素中的任何一个。在这篇综述中,我们讨论了流感病毒传播的许多方面,包括研究它的系统,以及自然屏障和各种非药物和药物干预的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Block the Spread: Barriers to Transmission of Influenza Viruses.

Respiratory viruses, such as influenza viruses, cause significant morbidity and mortality worldwide through seasonal epidemics and sporadic pandemics. Influenza viruses transmit through multiple modes including contact (either direct or through a contaminated surface) and inhalation of expelled aerosols. Successful human to human transmission requires an infected donor who expels virus into the environment, a susceptible recipient, and persistence of the expelled virus within the environment. The relative efficiency of each mode can be altered by viral features, environmental parameters, donor and recipient host characteristics, and viral persistence. Interventions to mitigate transmission of influenza viruses can target any of these factors. In this review, we discuss many aspects of influenza virus transmission, including the systems to study it, as well as the impact of natural barriers and various nonpharmaceutical and pharmaceutical interventions.

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来源期刊
CiteScore
19.40
自引率
0.90%
发文量
28
期刊介绍: The Annual Review of Virology serves as a conduit for disseminating thrilling advancements in our comprehension of viruses spanning animals, plants, bacteria, archaea, fungi, and protozoa. Its reviews illuminate novel concepts and trajectories in basic virology, elucidating viral disease mechanisms, exploring virus-host interactions, and scrutinizing cellular and immune responses to virus infection. These reviews underscore the exceptional capacity of viruses as potent probes for investigating cellular function.
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