Marika Bini Antunes , Sara Pinto Cardeal , Manuel Magalhães , Emídio Vale-Fernandes , Márcia Barreiro , Rosália Sá , Mário Sousa
{"title":"女性血液病患者生育能力的保存","authors":"Marika Bini Antunes , Sara Pinto Cardeal , Manuel Magalhães , Emídio Vale-Fernandes , Márcia Barreiro , Rosália Sá , Mário Sousa","doi":"10.1016/j.blre.2023.101115","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Recent developments of assisted reproduction techniques<span> turned possible to avoid the infertility consequences of oncologic treatments, but </span></span>fertility preservation<span> (FP) has been somewhat neglected in women with hematologic diseases undergoing gonadotoxic treatments. For these specific cases, the current options for FP include the </span></span>cryopreservation<span> of embryos, mature oocytes and ovarian tissue, and oocyte in-vitro maturation. We intend to make patients and clinicians aware of this important and relevant issue, and provide hematologists, assisted reproduction physicians and patients, with updated tools to guide decisions for FP. The physicians of the units responsible for female FP should always be available to decide on the best-individualized FP option in strict collaboration with hematologists. With a wide range of options for FP tailored to each case, a greater level of training and information is needed among clinicians, so that patients proposed to gonadotoxic treatments can be previously advised for FP techniques in hematological conditions.</span></p></div><div><h3>Abbreviated abstract</h3><p>Recent developments of assisted reproduction techniques turned possible to preserve the fertility of women with hematologic diseases undergoing gonadotoxic treatments.</p><p>Current options for fertility preservation in women with hematologic diseases are presented.</p><p>It is imperative to offer fertility preservation to all women before starting any gonadotoxic treatment and in some cases after treatment.</p><p>Fertility preservation methods enable to later achieve the desired pregnancy</p></div>","PeriodicalId":56139,"journal":{"name":"Blood Reviews","volume":null,"pages":null},"PeriodicalIF":6.9000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Preservation of fertility in female patients with hematologic diseases\",\"authors\":\"Marika Bini Antunes , Sara Pinto Cardeal , Manuel Magalhães , Emídio Vale-Fernandes , Márcia Barreiro , Rosália Sá , Mário Sousa\",\"doi\":\"10.1016/j.blre.2023.101115\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>Recent developments of assisted reproduction techniques<span> turned possible to avoid the infertility consequences of oncologic treatments, but </span></span>fertility preservation<span> (FP) has been somewhat neglected in women with hematologic diseases undergoing gonadotoxic treatments. For these specific cases, the current options for FP include the </span></span>cryopreservation<span> of embryos, mature oocytes and ovarian tissue, and oocyte in-vitro maturation. We intend to make patients and clinicians aware of this important and relevant issue, and provide hematologists, assisted reproduction physicians and patients, with updated tools to guide decisions for FP. The physicians of the units responsible for female FP should always be available to decide on the best-individualized FP option in strict collaboration with hematologists. With a wide range of options for FP tailored to each case, a greater level of training and information is needed among clinicians, so that patients proposed to gonadotoxic treatments can be previously advised for FP techniques in hematological conditions.</span></p></div><div><h3>Abbreviated abstract</h3><p>Recent developments of assisted reproduction techniques turned possible to preserve the fertility of women with hematologic diseases undergoing gonadotoxic treatments.</p><p>Current options for fertility preservation in women with hematologic diseases are presented.</p><p>It is imperative to offer fertility preservation to all women before starting any gonadotoxic treatment and in some cases after treatment.</p><p>Fertility preservation methods enable to later achieve the desired pregnancy</p></div>\",\"PeriodicalId\":56139,\"journal\":{\"name\":\"Blood Reviews\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":6.9000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Blood Reviews\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0268960X23000760\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Blood Reviews","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0268960X23000760","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEMATOLOGY","Score":null,"Total":0}
Preservation of fertility in female patients with hematologic diseases
Recent developments of assisted reproduction techniques turned possible to avoid the infertility consequences of oncologic treatments, but fertility preservation (FP) has been somewhat neglected in women with hematologic diseases undergoing gonadotoxic treatments. For these specific cases, the current options for FP include the cryopreservation of embryos, mature oocytes and ovarian tissue, and oocyte in-vitro maturation. We intend to make patients and clinicians aware of this important and relevant issue, and provide hematologists, assisted reproduction physicians and patients, with updated tools to guide decisions for FP. The physicians of the units responsible for female FP should always be available to decide on the best-individualized FP option in strict collaboration with hematologists. With a wide range of options for FP tailored to each case, a greater level of training and information is needed among clinicians, so that patients proposed to gonadotoxic treatments can be previously advised for FP techniques in hematological conditions.
Abbreviated abstract
Recent developments of assisted reproduction techniques turned possible to preserve the fertility of women with hematologic diseases undergoing gonadotoxic treatments.
Current options for fertility preservation in women with hematologic diseases are presented.
It is imperative to offer fertility preservation to all women before starting any gonadotoxic treatment and in some cases after treatment.
Fertility preservation methods enable to later achieve the desired pregnancy
期刊介绍:
Blood Reviews, a highly regarded international journal, serves as a vital information hub, offering comprehensive evaluations of clinical practices and research insights from esteemed experts. Specially commissioned, peer-reviewed articles authored by leading researchers and practitioners ensure extensive global coverage across all sub-specialties of hematology.