Sukran Dogru, Asli Altinordu Atci, Fatih Akkus, Arif Caner Erdogan, Ali Acar
{"title":"血液学参数在剖宫产瘢痕妊娠诊断中的可预测性。","authors":"Sukran Dogru, Asli Altinordu Atci, Fatih Akkus, Arif Caner Erdogan, Ali Acar","doi":"10.1055/s-0043-1761929","DOIUrl":null,"url":null,"abstract":"<p><p><b>Introduction</b> Cesarean scar pregnancy (CSP) is an increasing clinical condition that causes serious maternal morbidity and mortality. This study aimed to evaluate if inflammation markers measured by hemogram can aid in the diagnosis of CSP. <b>Materials and Methods</b> A total of 86 patients were included in the study. The cases were divided as CSP ( <i>n</i> : 42) and normal pregnancy (NP) ( <i>n</i> : 44). At the time of admission, peripheral blood neutrophils, lymphocytes, monocytes, thrombocytes, systemic inflammatory index (SII) (neutrophil × platelet/lymphocyte), neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio, and platelet-lymphocyte ratio were all measured. CSP and NP diagnoses were made by transabdominal or vaginal ultrasonography. <b>Results</b> In the CSP group, mean age ( <i>p</i> < 0.001), gravida ( <i>p</i> < 0.001), parity ( <i>p</i> < 0.001), number of surviving children ( <i>p</i> < 0.001), number of abortions ( <i>p</i> < 0.001), cesarean number ( <i>p</i> < .001), dilatation and curettage count ( <i>p</i> = 0.013), monocyte (M) value ( <i>p</i> = 0.039) and monocyte/lymphocyte value (MLR) ( <i>p</i> = 0.035) were significantly higher than the control group. The optimal M value cut-off value was found to be > 0.40, the sensitivity value was 78.57, and the specificity value was 50.00. AUC = 0.632 (SE = 0.061) for the MLR value. The optimal MLR cut-off value was found to be > 0.232, the sensitivity value was 61.90, and the specificity value was 63.64. <b>Conclusion</b> Hemogram parameters, which are simple, inexpensive, and easily accessible, M and MLR are significantly higher in the diagnosis of CSP and can be used as an auxiliary parameter for ultrasonography.</p>","PeriodicalId":16149,"journal":{"name":"Journal of Laboratory Physicians","volume":"15 3","pages":"425-430"},"PeriodicalIF":0.9000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/f0/10-1055-s-0043-1761929.PMC10411160.pdf","citationCount":"0","resultStr":"{\"title\":\"Predictability of Hematological Parameters in the Diagnosis of Cesarean Scar Pregnancy.\",\"authors\":\"Sukran Dogru, Asli Altinordu Atci, Fatih Akkus, Arif Caner Erdogan, Ali Acar\",\"doi\":\"10.1055/s-0043-1761929\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Introduction</b> Cesarean scar pregnancy (CSP) is an increasing clinical condition that causes serious maternal morbidity and mortality. This study aimed to evaluate if inflammation markers measured by hemogram can aid in the diagnosis of CSP. <b>Materials and Methods</b> A total of 86 patients were included in the study. The cases were divided as CSP ( <i>n</i> : 42) and normal pregnancy (NP) ( <i>n</i> : 44). At the time of admission, peripheral blood neutrophils, lymphocytes, monocytes, thrombocytes, systemic inflammatory index (SII) (neutrophil × platelet/lymphocyte), neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio, and platelet-lymphocyte ratio were all measured. CSP and NP diagnoses were made by transabdominal or vaginal ultrasonography. <b>Results</b> In the CSP group, mean age ( <i>p</i> < 0.001), gravida ( <i>p</i> < 0.001), parity ( <i>p</i> < 0.001), number of surviving children ( <i>p</i> < 0.001), number of abortions ( <i>p</i> < 0.001), cesarean number ( <i>p</i> < .001), dilatation and curettage count ( <i>p</i> = 0.013), monocyte (M) value ( <i>p</i> = 0.039) and monocyte/lymphocyte value (MLR) ( <i>p</i> = 0.035) were significantly higher than the control group. The optimal M value cut-off value was found to be > 0.40, the sensitivity value was 78.57, and the specificity value was 50.00. AUC = 0.632 (SE = 0.061) for the MLR value. The optimal MLR cut-off value was found to be > 0.232, the sensitivity value was 61.90, and the specificity value was 63.64. <b>Conclusion</b> Hemogram parameters, which are simple, inexpensive, and easily accessible, M and MLR are significantly higher in the diagnosis of CSP and can be used as an auxiliary parameter for ultrasonography.</p>\",\"PeriodicalId\":16149,\"journal\":{\"name\":\"Journal of Laboratory Physicians\",\"volume\":\"15 3\",\"pages\":\"425-430\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/f0/10-1055-s-0043-1761929.PMC10411160.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Laboratory Physicians\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0043-1761929\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Laboratory Physicians","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0043-1761929","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
剖宫产瘢痕妊娠(CSP)是一种日益严重的临床疾病,可导致严重的产妇发病率和死亡率。本研究旨在评价血象中炎症标志物的测定是否有助于CSP的诊断。材料与方法共纳入86例患者。病例分为CSP(42例)和正常妊娠(NP)(44例)。入院时测定外周血中性粒细胞、淋巴细胞、单核细胞、血小板、全身炎症指数(SII)(中性粒细胞×血小板/淋巴细胞)、中性粒细胞-淋巴细胞比值、单核细胞-淋巴细胞比值、血小板-淋巴细胞比值。经腹或阴道超声诊断CSP和NP。结果CSP组患者的平均年龄(p p p p p p p = 0.013)、单核细胞(M)值(p = 0.039)、单核细胞/淋巴细胞值(MLR) (p = 0.035)均显著高于对照组。最佳M值临界值> 0.40,敏感性值为78.57,特异性值为50.00。MLR值的AUC = 0.632 (SE = 0.061)。最佳MLR临界值> 0.232,敏感性值为61.90,特异性值为63.64。结论M、MLR对CSP的诊断价值明显高于其他血象参数,可作为超声检查的辅助参数,其简单、廉价、易得。
Predictability of Hematological Parameters in the Diagnosis of Cesarean Scar Pregnancy.
Introduction Cesarean scar pregnancy (CSP) is an increasing clinical condition that causes serious maternal morbidity and mortality. This study aimed to evaluate if inflammation markers measured by hemogram can aid in the diagnosis of CSP. Materials and Methods A total of 86 patients were included in the study. The cases were divided as CSP ( n : 42) and normal pregnancy (NP) ( n : 44). At the time of admission, peripheral blood neutrophils, lymphocytes, monocytes, thrombocytes, systemic inflammatory index (SII) (neutrophil × platelet/lymphocyte), neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio, and platelet-lymphocyte ratio were all measured. CSP and NP diagnoses were made by transabdominal or vaginal ultrasonography. Results In the CSP group, mean age ( p < 0.001), gravida ( p < 0.001), parity ( p < 0.001), number of surviving children ( p < 0.001), number of abortions ( p < 0.001), cesarean number ( p < .001), dilatation and curettage count ( p = 0.013), monocyte (M) value ( p = 0.039) and monocyte/lymphocyte value (MLR) ( p = 0.035) were significantly higher than the control group. The optimal M value cut-off value was found to be > 0.40, the sensitivity value was 78.57, and the specificity value was 50.00. AUC = 0.632 (SE = 0.061) for the MLR value. The optimal MLR cut-off value was found to be > 0.232, the sensitivity value was 61.90, and the specificity value was 63.64. Conclusion Hemogram parameters, which are simple, inexpensive, and easily accessible, M and MLR are significantly higher in the diagnosis of CSP and can be used as an auxiliary parameter for ultrasonography.