{"title":"高血压是原发性开角型青光眼的危险因素:荟萃分析。","authors":"Jianjun Wu, Hailong Wang, Shimei Yu","doi":"10.29271/jcpsp.2023.08.915","DOIUrl":null,"url":null,"abstract":"<p><p>Hypertension (HTN) is not recognised as an independent risk factor for primary open-angle glaucoma (POAG). A search of PubMed, Embase, Medline, Wanfang, and Cochrane Library databases from the time each database was established up to July 2022 was performed. All studies were pooled and assessed for heterogeneity and the quality of the literature. Five cross-sectional studies were included in the meta-analysis with 1144 individuals with POAG and 29, 373 without POAG. The combined analysis found that the incidence of HTN was higher among the individuals with POAG than among those without (OR 1.55; p <0.001). There was also a significant difference in the incidence of diabetes among individuals with POAG compared with those without (OR: 1.31; p=0.002). A meta-analysis of cross-sectional studies revealed that the incidence of HTN and diabetes was significantly greater among individuals with POAG. HTN and diabetes were found to be independent risk factors for POAG. Key Words: Primary open-angle glaucoma (POAG), Hypertension (HTN), Diabetes, Meta-analysis.</p>","PeriodicalId":54905,"journal":{"name":"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan","volume":"33 8","pages":"915-918"},"PeriodicalIF":0.7000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hypertension as a Risk Factor for Primary Open-angle Glaucoma: A Meta-analysis.\",\"authors\":\"Jianjun Wu, Hailong Wang, Shimei Yu\",\"doi\":\"10.29271/jcpsp.2023.08.915\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Hypertension (HTN) is not recognised as an independent risk factor for primary open-angle glaucoma (POAG). A search of PubMed, Embase, Medline, Wanfang, and Cochrane Library databases from the time each database was established up to July 2022 was performed. All studies were pooled and assessed for heterogeneity and the quality of the literature. Five cross-sectional studies were included in the meta-analysis with 1144 individuals with POAG and 29, 373 without POAG. The combined analysis found that the incidence of HTN was higher among the individuals with POAG than among those without (OR 1.55; p <0.001). There was also a significant difference in the incidence of diabetes among individuals with POAG compared with those without (OR: 1.31; p=0.002). A meta-analysis of cross-sectional studies revealed that the incidence of HTN and diabetes was significantly greater among individuals with POAG. HTN and diabetes were found to be independent risk factors for POAG. Key Words: Primary open-angle glaucoma (POAG), Hypertension (HTN), Diabetes, Meta-analysis.</p>\",\"PeriodicalId\":54905,\"journal\":{\"name\":\"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan\",\"volume\":\"33 8\",\"pages\":\"915-918\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2023-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.29271/jcpsp.2023.08.915\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.29271/jcpsp.2023.08.915","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Hypertension as a Risk Factor for Primary Open-angle Glaucoma: A Meta-analysis.
Hypertension (HTN) is not recognised as an independent risk factor for primary open-angle glaucoma (POAG). A search of PubMed, Embase, Medline, Wanfang, and Cochrane Library databases from the time each database was established up to July 2022 was performed. All studies were pooled and assessed for heterogeneity and the quality of the literature. Five cross-sectional studies were included in the meta-analysis with 1144 individuals with POAG and 29, 373 without POAG. The combined analysis found that the incidence of HTN was higher among the individuals with POAG than among those without (OR 1.55; p <0.001). There was also a significant difference in the incidence of diabetes among individuals with POAG compared with those without (OR: 1.31; p=0.002). A meta-analysis of cross-sectional studies revealed that the incidence of HTN and diabetes was significantly greater among individuals with POAG. HTN and diabetes were found to be independent risk factors for POAG. Key Words: Primary open-angle glaucoma (POAG), Hypertension (HTN), Diabetes, Meta-analysis.
期刊介绍：
Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991.
Established with the primary aim of promotion and dissemination of medical research and contributed by scholars of biomedical sciences from Pakistan and abroad, it carries original research papers, , case reports, review articles, articles on medical education, commentaries, short communication, new technology, editorials and letters to the editor. It covers the core biomedical health science subjects, basic medical sciences and emerging community problems, prepared in accordance with the “Uniform requirements for submission to bio-medical journals” laid down by International Committee of Medical Journals Editors (ICMJE). All publications of JCPSP are peer reviewed by subject specialists from Pakistan and locally and abroad.
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