天然药物的工业全合成。

IF 12.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

ACS Central Science Pub Date : 2023-11-15 DOI:10.1039/d3np00020f

Xiao-Yu Liu , Yong Qin

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引用次数: 0

摘要

如果由于天然丰度低或缺乏有效的发酵或半合成方法而无法获得足够数量的天然药物，则全合成提供了生产天然药物的关键方法。本观点概述了过去和目前的研究状况，因为它们适用于工业规模的天然药物全合成，并提供了该领域未来发展潜力的整体观点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Industrial total synthesis of natural medicines

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Industrial total synthesis of natural medicines

Total synthesis offers a key approach to the production of natural medicines if sufficient quantities cannot be obtained due to low natural abundance or lack of efficient fermentation or semi-synthesis methods. This Viewpoint outlines the previous and current states of research as they apply to the total synthesis of natural medicines on an industrial scale and provides a holistic view on the potential for future developments in the field.

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来源期刊

ACS Central Science Chemical Engineering-General Chemical Engineering

CiteScore

25.50

自引率

0.50%

发文量

194

审稿时长

10 weeks

期刊介绍： ACS Central Science publishes significant primary reports on research in chemistry and allied fields where chemical approaches are pivotal. As the first fully open-access journal by the American Chemical Society, it covers compelling and important contributions to the broad chemistry and scientific community. "Central science," a term popularized nearly 40 years ago, emphasizes chemistry's central role in connecting physical and life sciences, and fundamental sciences with applied disciplines like medicine and engineering. The journal focuses on exceptional quality articles, addressing advances in fundamental chemistry and interdisciplinary research.