在韩国首尔销售的指甲化妆品中重金属的测定和风险评估。

IF 1.6 4区医学 Q3 OPHTHALMOLOGY

Cutaneous and Ocular Toxicology Pub Date : 2023-09-01 DOI:10.1080/15569527.2023.2223285

Suun Kim, Chaeman Choi, Myeongsook Lee, Insook Hwang

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引用次数: 0

摘要

目的:本研究的目的是评估在韩国首尔市销售的指甲化妆品的一些毒性水平和对人体的健康风险评估。方法:随机抽取45件美甲化妆品，采用电感耦合等离子体发射光谱法(ICP-OES)对化妆品中铅、镉、砷、锑的含量进行分析。结果:4种金属浓度分别为Pb 0.037±0.083 (p)。讨论与结论:6种指甲化妆品的锑含量均高于韩国现行法定限量。由于6个锑浓度较高，MoS、HQ、HI均不在可接受范围内。铅、砷、镉的LCR值低于10 ~ 6，低于允许限值，指甲化妆品可能不具有终身癌症风险。我们的研究结果表明，金属在指甲化妆品中以不同的浓度存在，一些指甲化妆品似乎对健康造成有害影响。

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Determination of heavy metals and risk assessment in nail cosmetics sold in Seoul, Korea.

Objective: The objective of this study was to evaluate some toxic levels of nail cosmetics marketed in Seoul, Korea and health risk assessment on humans.

Methods: We collected 45 random nail cosmetics and analysed for lead, cadmium, arsenic and antimony by inductively coupled plasma-optical emission spectrometry (ICP-OES).

Results: Four metals concentrations were Pb 0.037 ± 0.083 (p < 0.05) and Sb concentrations in 6 samples were above the acceptable limits in Korea. As the result of the health risk assessment, MoS, HQ and HI values for Pb, As and Cd were within the permissible limit, but outside the acceptable range of Sb. LCR value was lower than the allowed limit for all nail cosmetics.

Discussion and conclusion: Six nail cosmetics had high antimony concentrations which were higher than the current legal limit in Korea. Because of 6 high antimony concentrations, MoS, HQ and HI were outside the acceptable range. LCR value for Pb, As and Cd was below 1 0 ^-6 which was lower than the permissible limit and nail cosmetics may not possess lifetime cancer risk. Our results suggested that metals were present in nail cosmetics at diverse concentrations and some nail cosmetics appeared to pose a harmful impact on health.

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来源期刊

Cutaneous and Ocular Toxicology 医学-毒理学

CiteScore

3.30

自引率

6.20%

发文量

审稿时长

1 months

期刊介绍： Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures. In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.