临床成纤维细胞-ILC2生态位抑制肝纤维化

IF 67.7 1区医学 Q1 IMMUNOLOGY

Nature Reviews Immunology Pub Date : 2023-06-27 DOI:10.1038/s41577-023-00909-2

Anthony Altieri, Matthew B. Buechler

引用次数: 0

摘要

Sbierski-Kind等人的预印本显示，产生IL-33的临床成纤维细胞为ILC2提供了一个基质位，从而限制了IL-17介导的肝纤维化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Adventitial fibroblast–ILC2 niche restrains liver fibrosis

A preprint by Sbierski-Kind et al. shows that IL-33-producing adventitial fibroblasts provide a stromal niche for ILC2s that limits IL-17-mediated liver fibrosis.

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来源期刊

Nature Reviews Immunology 医学-免疫学

CiteScore

93.40

自引率

0.40%

发文量

131

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Immunology is a journal that provides comprehensive coverage of all areas of immunology, including fundamental mechanisms and applied aspects. It has two international standard serial numbers (ISSN): 1474-1733 for print and 1474-1741 for online. In addition to review articles, the journal also features recent developments and new primary papers in the field, as well as reflections on influential people, papers, and events in the development of immunology. The subjects covered by Nature Reviews Immunology include allergy and asthma, autoimmunity, antigen processing and presentation, apoptosis and cell death, chemokines and chemokine receptors, cytokines and cytokine receptors, development and function of cells of the immune system, haematopoiesis, infection and immunity, immunotherapy, innate immunity, mucosal immunology and the microbiota, regulation of the immune response, signalling in the immune system, transplantation, tumour immunology and immunotherapy, and vaccine development.