多发性肌炎和皮肌炎的心脏受累:诊断方法。

IF 1.4 Q3 RHEUMATOLOGY
Reumatologia Pub Date : 2023-01-01 Epub Date: 2023-07-02 DOI:10.5114/reum/168362
Agnieszka Trybuch, Beata Tarnacka
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引用次数: 0

摘要

多发性肌炎(PM)和皮肌炎(DM)是罕见的特发性炎症性肌病(IIM)。IIM患者的心肌受累是一个不利的预后因素,也是该组患者最常见的死亡原因之一。这篇综述的目的是介绍在IIM中观察到的心血管表现的最新知识。选择截至2021年12月以英文发布的数据。提示心脏受累的临床症状是非特异性的,需要根据心脏病学指南进行鉴别诊断。肌钙蛋白I对心脏损伤具有特异性,应优先于其他标志物来评估IIM中的心肌。心电图异常在IIM中很常见,尤其是ST-T段的非特异性变化。在标准超声心动图中,经常报告左心室舒张功能障碍。新的诊断技术可以揭示临床上无症状的心肌异常。然而,亚临床心肌功能损害的预后价值还需要进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Cardiac involvement in polymyositis and dermatomyositis: diagnostic approaches.

Cardiac involvement in polymyositis and dermatomyositis: diagnostic approaches.

Cardiac involvement in polymyositis and dermatomyositis: diagnostic approaches.

Polymyositis (PM) and dermatomyositis (DM) are rare idiopathic inflammatory myopathies (IIM). Myocardial involvement in patients with IIM is an unfavorable prognostic factor and one of the most common cause of mortality in this group of patients. The purpose of this review is to present current knowledge on cardiovascular manifestations observed in IIM. Data published in English until December 2021 were selected. Clinical symptoms suggesting cardiac involvement are non-specific and require a differential diagnosis in accordance with cardiological guidelines. Troponin I is specific to cardiac injury and should be preferred to other markers to evaluate the myocardium in IIM. Abnormalities in electrocardiography are common in IIM, especially non-specific changes of the ST-T segment. In standard echocardiography left ventricular diastolic dysfunction is reported frequently. New diagnostic technologies can reveal clinically silent myocardial abnormalities. However, the prognostic value of subclinical impairment of myocardial function require further studies.

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来源期刊
Reumatologia
Reumatologia Medicine-Rheumatology
CiteScore
2.70
自引率
0.00%
发文量
44
审稿时长
10 weeks
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