前交叉韧带修复:继续探索(博士学院奖)。

IF 3.5 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

ACS Chemical Biology Pub Date : 2023-08-01 DOI:10.1136/bjsports-2022-106674

Roy Hoogeslag

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Anterior cruciate ligament repair: the quest continues (PhD Academy Award).

© Author(s) (or their employer(s)) 2023. No commercial reuse. See rights and permissions. Published by BMJ. WHAT DID I DO? I investigated the role of modern anterior cruciate ligament (ACL) suture repair (ACLSR) in the treatment of ACL ruptures (ACL#). The aims were (1) to systematically review the literature on the clinical outcomes of ACLSR techniques; (2) to investigate the role of bracing of the ACLSR with a strong smalldiameter braid that is positioned parallel to the repaired ACL (augmentation) to negate residual anterior translation forces during early rehabilitation; (3) to assess the early and midterm outcomes of dynamic augmented ACLSR in relation to the current surgical gold standard, ACL reconstruction (ACLR) with an autologous tendon graft and (4) to assess the role of MRI in determining ACL# morphology.

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来源期刊

ACS Chemical Biology 生物-生化与分子生物学

CiteScore

7.50

自引率

5.00%

发文量

353

审稿时长

3.3 months

期刊介绍： ACS Chemical Biology provides an international forum for the rapid communication of research that broadly embraces the interface between chemistry and biology. The journal also serves as a forum to facilitate the communication between biologists and chemists that will translate into new research opportunities and discoveries. Results will be published in which molecular reasoning has been used to probe questions through in vitro investigations, cell biological methods, or organismic studies. We welcome mechanistic studies on proteins, nucleic acids, sugars, lipids, and nonbiological polymers. The journal serves a large scientific community, exploring cellular function from both chemical and biological perspectives. It is understood that submitted work is based upon original results and has not been published previously.