表观扩散系数是否被确定为肝细胞癌立体定向放射治疗评估的成像生物标志物？

IF 2.6 4区医学 Q3 ONCOLOGY

Cancer journal Pub Date : 2023-07-01 DOI:10.1097/PPO.0000000000000668

Yue Cao, Kyle C Cuneo, Joseph Evans, Randall K Ten Haken, Daniel T Chang, Theodore S Lawrence

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引用次数: 0

摘要

摘要：在这篇文章中，作为早期反应生物标志物特刊的一部分，我们回顾了目前关于肝细胞癌（HCC）在立体定向身体放射治疗后磁共振成像表观扩散系数（ADC）变化的报道。我们比较了扩散图像采集、ADC分析、HCC反应评估方法以及通过ADC指标预测局部肿瘤进展的统计方法。我们讨论了这些研究的利弊。根据对现有研究的详细分析，我们不能得出ADC被确定为HCC立体定向身体放射治疗评估的成像生物标志物的结论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Is Apparent Diffusion Coefficient Established as an Imaging Biomarker for Stereotactic Body Radiation Therapy Assessment in Hepatocellular Carcinoma?

Abstract: In this article, as part of this special issue on biomarkers of early response, we review currently available reports regarding magnetic resonance imaging apparent diffusion coefficient (ADC) changes in hepatocellular carcinoma (HCC) in response to stereotactic body radiation therapy. We compare diffusion image acquisition, ADC analysis, methods for HCC response assessment, and statistical methods for prediction of local tumor progression by ADC metrics. We discuss the pros and cons of these studies. Following detailed analyses of existing investigations, we cannot conclude that ADC is established as an imaging biomarker for stereotactic body radiation therapy assessment in HCC.

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来源期刊

Cancer journal 医学-肿瘤学

CiteScore

3.90

自引率

0.00%

发文量

102

审稿时长

7.5 months

期刊介绍： The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.