疫苗在应对 COVID-19 大流行中的作用

IF 2.7 4区生物学 Q2 BIOCHEMICAL RESEARCH METHODS

SLAS Discovery Pub Date : 2023-12-01 DOI:10.1016/j.slasd.2023.07.002

Professor Dr. Batool Mutar Mahdi , Dr. Mustafa Almukhtar

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引用次数: 0

摘要

冠状病毒（CoV）是感染人类的最大病毒家族之一，可引起轻微的普通感冒或中东呼吸综合征（MERS-CoV）和严重急性呼吸综合征（SARS-CoV）等严重疾病。一种被称为新型冠状病毒（nCoV）的新病毒株出现了，它可导致致命的呼吸衰竭疾病。这种病毒的特点是迅速从无症状和有症状的病人向健康人传播。因此，疫苗应被视为控制这种病毒传播的重要保护措施之一。这种疫苗面临的挑战之一是这种病毒的高变异率和新毒株的出现。因此，疫苗应刺激免疫系统，以克服新病毒株的出现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Role Of Vaccines Against COVID-19 Pandemic

Coronaviruses (CoV) are one of the largest families of viruses that infect human beings causing mild common cold or severe diseases like Middle East Respiratory Syndrome (MERS-CoV), and Severe Acute Respiratory Syndrome (SARS-CoV). A new strain emerged known as novel coronavirus (nCoV) causing fatal respiratory failure disease. This virus was characterized by rapid spread from asymptomatic and symptomatic patients to healthy people. Thus, vaccine should be considered as one of the important protective measures to control the spread of this virus. One of the challenges to this vaccine is the high mutation rate of this virus and appearance of new strains. Therefore, vaccine should stimulate the immune system in order to overcome the emergence of new strain of this virus.

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来源期刊

SLAS Discovery Chemistry-Analytical Chemistry

CiteScore

7.00

自引率

3.20%

发文量

审稿时长

39 days

期刊介绍： Advancing Life Sciences R&D: SLAS Discovery reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease. SLAS Discovery is a peer-reviewed journal that publishes scientific reports that enable and improve target validation, evaluate current drug discovery technologies, provide novel research tools, and incorporate research approaches that enhance depth of knowledge and drug discovery success. SLAS Discovery emphasizes scientific and technical advances in target identification/validation (including chemical probes, RNA silencing, gene editing technologies); biomarker discovery; assay development; virtual, medium- or high-throughput screening (biochemical and biological, biophysical, phenotypic, toxicological, ADME); lead generation/optimization; chemical biology; and informatics (data analysis, image analysis, statistics, bio- and chemo-informatics). Review articles on target biology, new paradigms in drug discovery and advances in drug discovery technologies. SLAS Discovery is of particular interest to those involved in analytical chemistry, applied microbiology, automation, biochemistry, bioengineering, biomedical optics, biotechnology, bioinformatics, cell biology, DNA science and technology, genetics, information technology, medicinal chemistry, molecular biology, natural products chemistry, organic chemistry, pharmacology, spectroscopy, and toxicology. SLAS Discovery is a member of the Committee on Publication Ethics (COPE) and was published previously (1996-2016) as the Journal of Biomolecular Screening (JBS).