[正常压力脑积水和阿尔茨海默病的并发：治疗意义和悬而未决的问题]。

IF 0.6 4区医学 Q4 CLINICAL NEUROLOGY

Fortschritte Der Neurologie Psychiatrie Pub Date : 2023-10-01 Epub Date: 2023-07-06 DOI:10.1055/a-2107-9983

Max Hubert, Patricia Homeyer, Moritz D Brandt, Markus Donix, Robert Haußmann

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引用次数: 0

摘要

正常压力性脑积水（NPH）在老年患者群体中普遍存在。尽管NPH具有临床相关性，但许多患者可能没有得到足够的治疗。由于阿尔茨海默病在这些患者中的频率，可能存在尚未完全理解的重叠病理生理机制。大脑合并症似乎对脑室-腹腔分流术的治疗反应有负面影响。为了避免对高度脆弱的老年患者进行不必要和不成功的手术，在诊断过程中必须考虑他们。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Coincidence of normal pressure hydrocephalus and Alzheimer`s disease: therapeutic implications and open questions].

Normal pressure hydrocephalus (NPH) is prevalent in aging patient populations. Despite its clinical relevance, many patients with NPH may not receive adequate treatment. Because of the frequency of Alzheimer`s disease in these patients, there could be overlapping pathophysiological mechanisms that are as yet incompletely understood. Cerebral comorbidities seem to have negative effects on therapeutic response to ventriculoperitoneal shunting. In order to avoid unnecessary and unsuccessful surgery in highly vulnerable elderly patients, they have to be taken into consideration in the diagnostic process.

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来源期刊

Fortschritte Der Neurologie Psychiatrie 医学-精神病学

CiteScore

1.10

自引率

16.70%

发文量

139

审稿时长

6-12 weeks

期刊介绍： Fundiertes Wissen für den Berufsalltag Relevante Originalarbeiten Informative Übersichten zu wichtigen Themen Fortbildungsteil mit Zertifizierung – 36 CME-Punkte pro Jahr Interessante Kasuistiken Referiert & kommentiert: Internationale Studien Aktuelles zu Begutachtung und Neurobiologie International gelistet und häufig zitiert