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引用次数: 0
摘要
综述的目的:本综述旨在阐明评估骨组织材料特性的新技术:最近,研究骨组织材料特性的方法越来越多。一直以来,临床医生在治疗骨质疏松症患者时都依赖于使用双能 X 射线吸收测量法(DXA)评估骨矿物质密度(BMD)。虽然 DXA 能够在大规模人群中进行筛查,但它只能解释约 60% 的骨折风险。小结:这些较新的技术尚未达到用于人群筛查的程度;不过,它们可能会为骨生物学科学提供更多信息,并有助于分辨各种骨病状态。
Novel techniques for assessment of bone tissue material properties.
Purpose of review: The purpose of this review will be to shed light on novel techniques for assessment of bone tissue material properties.
Recent findings: Recently there has been an increase in modalities to investigate bone tissue material properties. Historically, clinicians treating patients with bone disorders have relied upon the use of bone mineral density (BMD) as assessed by dual-energy X-ray absorptiometry (DXA). Although DXA provides an ability to screen at a large-scale population level, it only explains about 60% of the fracture risk. Recent advances include the use of imaging modalities, responses to load, and novel infrared (IR) techniques.
Summary: These newer techniques have not reached a point for population level screening; however, they may inform the science of bone biology further and help discern various bone disease states.
期刊介绍:
Current Opinion in Endocrinology, Diabetes and Obesity delivers a broad-based perspective on the most recent and exciting developments in the field from across the world. Published bimonthly and featuring twelve key topics – including androgens, gastrointestinal hormones, diabetes and the endocrine pancreas, and neuroendocrinology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.