{"title":"【现代肿瘤治疗及其肺副反应】。","authors":"Katharina Hellbach","doi":"10.1007/s00117-021-00912-5","DOIUrl":null,"url":null,"abstract":"<p><p>Radiation therapy and more recently, drug-based molecular therapy in particular, are a central component of modern oncology. Both forms of therapy are suitable for effectively treating tumors with comparatively low systemic side effects. Nevertheless, even these treatment approaches have side effects, which are triggered by the toxicity of the radiation and by the immunomodulatory effects of the administered drugs. The pneumotoxic potential of these forms of therapy is reflected in the development of interstitial pneumonitis, which can transition into fibrotic changes in the lung structure. The clinical diagnosis of the disease is made more difficult as the symptoms are nonspecific. Computed tomography (CT) is an excellent means of diagnosing the corresponding consolidations and to monitor them over time. Therefore, in the interdisciplinary context the radiologist plays a central role in the diagnostics of this disease.</p>","PeriodicalId":54513,"journal":{"name":"Radiologe","volume":"61 10","pages":"955-967"},"PeriodicalIF":0.0000,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456401/pdf/","citationCount":"0","resultStr":"{\"title\":\"[Modern tumor therapy and its pulmonary side effects].\",\"authors\":\"Katharina Hellbach\",\"doi\":\"10.1007/s00117-021-00912-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Radiation therapy and more recently, drug-based molecular therapy in particular, are a central component of modern oncology. Both forms of therapy are suitable for effectively treating tumors with comparatively low systemic side effects. Nevertheless, even these treatment approaches have side effects, which are triggered by the toxicity of the radiation and by the immunomodulatory effects of the administered drugs. The pneumotoxic potential of these forms of therapy is reflected in the development of interstitial pneumonitis, which can transition into fibrotic changes in the lung structure. The clinical diagnosis of the disease is made more difficult as the symptoms are nonspecific. Computed tomography (CT) is an excellent means of diagnosing the corresponding consolidations and to monitor them over time. Therefore, in the interdisciplinary context the radiologist plays a central role in the diagnostics of this disease.</p>\",\"PeriodicalId\":54513,\"journal\":{\"name\":\"Radiologe\",\"volume\":\"61 10\",\"pages\":\"955-967\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456401/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiologe\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00117-021-00912-5\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiologe","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00117-021-00912-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
[Modern tumor therapy and its pulmonary side effects].
Radiation therapy and more recently, drug-based molecular therapy in particular, are a central component of modern oncology. Both forms of therapy are suitable for effectively treating tumors with comparatively low systemic side effects. Nevertheless, even these treatment approaches have side effects, which are triggered by the toxicity of the radiation and by the immunomodulatory effects of the administered drugs. The pneumotoxic potential of these forms of therapy is reflected in the development of interstitial pneumonitis, which can transition into fibrotic changes in the lung structure. The clinical diagnosis of the disease is made more difficult as the symptoms are nonspecific. Computed tomography (CT) is an excellent means of diagnosing the corresponding consolidations and to monitor them over time. Therefore, in the interdisciplinary context the radiologist plays a central role in the diagnostics of this disease.
期刊介绍:
Der Radiologe is an internationally recognized journal dealing with all aspects of radiology and serving the continuing medical education of radiologists in clinical and practical environments. The focus is on x-ray diagnostics, angiography computer tomography, interventional radiology, magnet resonance tomography, digital picture processing, radio oncology and nuclear medicine.
Comprehensive reviews on a specific topical issue focus on providing evidenced based information on diagnostics and therapy.
Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange.
Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.