两性两性社会行为的神经控制:将发育与成年联系起来。

IF 12.1 1区 医学 Q1 NEUROSCIENCES
Margaret M McCarthy
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引用次数: 2

摘要

社会行为神经控制的快速发展突出了参与差异信息处理以产生行为的互联节点的作用。许多天生的社会行为对生殖健康至关重要,因此在男性和女性中存在根本差异。编程这些差异发生在哺乳动物发育的早期,在性腺分化和胎儿睾丸在关键时期产生大量雄激素之后。社会行为的早期编程和它的成年表现是分开但相互关联的过程,但它们是如何联系在一起的尚不清楚。这篇综述试图通过确定四种核心机制(表观遗传学、细胞死亡、电路形成和成人激素调节)来强调这一差距,这些机制可能将发育变化与成人的交配和攻击行为联系起来。我们进一步提出,一种独特的社会行为,青少年游戏,通过参与支持成人繁殖和攻击行为的相同神经网络,架起了断奶前和青春期后大脑的桥梁。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neural Control of Sexually Dimorphic Social Behavior: Connecting Development to Adulthood.

Rapid advances in the neural control of social behavior highlight the role of interconnected nodes engaged in differential information processing to generate behavior. Many innate social behaviors are essential to reproductive fitness and therefore fundamentally different in males and females. Programming these differences occurs early in development in mammals, following gonadal differentiation and copious androgen production by the fetal testis during a critical period. Early-life programming of social behavior and its adult manifestation are separate but yoked processes, yet how they are linked is unknown. This review seeks to highlight that gap by identifying four core mechanisms (epigenetics, cell death, circuit formation, and adult hormonal modulation) that could connect developmental changes to the adult behaviors of mating and aggression. We further propose that a unique social behavior, adolescent play, bridges the preweaning to the postpubertal brain by engaging the same neural networks underpinning adult reproductive and aggressive behaviors.

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来源期刊
Annual review of neuroscience
Annual review of neuroscience 医学-神经科学
CiteScore
25.30
自引率
0.70%
发文量
29
期刊介绍: The Annual Review of Neuroscience is a well-established and comprehensive journal in the field of neuroscience, with a rich history and a commitment to open access and scholarly communication. The journal has been in publication since 1978, providing a long-standing source of authoritative reviews in neuroscience. The Annual Review of Neuroscience encompasses a wide range of topics within neuroscience, including but not limited to: Molecular and cellular neuroscience, Neurogenetics, Developmental neuroscience, Neural plasticity and repair, Systems neuroscience, Cognitive neuroscience, Behavioral neuroscience, Neurobiology of disease. Occasionally, the journal also features reviews on the history of neuroscience and ethical considerations within the field.
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