circRNA 在家畜育种相关性状中的新作用。

IF 6.4 2区 生物学 Q1 CELL BIOLOGY
Wiley Interdisciplinary Reviews: RNA Pub Date : 2023-07-01 Epub Date: 2023-01-11 DOI:10.1002/wrna.1775
Ping Sun, Mengjie Chen, Suren R Sooranna, Deshun Shi, Qingyou Liu, Hui Li
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引用次数: 0

摘要

许多指标可用于评估牲畜的生产率和质量,如产肉量和产奶量以及脂肪沉积。产肉量和产奶量是衡量家畜性能的指标,而脂肪沉积则会影响肉的口感和风味。circRNA 是一种非编码 RNA,参与了上述三种性状的调控。我们回顾了 circRNA 在肌肉和脂肪发育以及泌乳过程中的功能和机制,为畜牧业中的 circRNA 研究提供理论基础。家畜的各种表型变化可能是由不同的 circRNA 产生的。我们目前关心的问题是如何利用 circRNAs 发挥的作用,使其成为我们的优势,从而生产出最好的家畜。因此,我们介绍了 circRNAs 基因敲除技术的优缺点。此外,我们还就 circRNAs 的机制和网络提出了自己的想法,以便为研究人员提供分子生物学如何帮助我们实现畜牧业目标的新思路。本文归类于RNA 在疾病和发育中的作用 > RNA 在疾病中的作用 RNA 与蛋白质和其他分子的相互作用 > 蛋白质与 RNA 的相互作用:RNA 与蛋白质及其他分子的相互作用 > 蛋白质-RNA 识别 RNA 与蛋白质及其他分子的相互作用 > RNA 蛋白复合物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The emerging roles of circRNAs in traits associated with livestock breeding.

The emerging roles of circRNAs in traits associated with livestock breeding.

Many indicators can be used to evaluate the productivity and quality of livestock, such as meat and milk production as well as fat deposition. Meat and milk production are measures of livestock performance, while fat deposition affects the taste and flavor of the meat. The circRNAs, are non-coding RNAs, that are involved in the regulation of all these three traits. We review the functions and mechanisms of circRNAs in muscle and fat development as well as lactation to provide a theoretical basis for circRNA research in animal husbandry. Various phenotypic changes presented in livestock may be produced by different circRNAs. Our current concern is how to use the roles played by circRNAs to our advantage to produce the best possible livestock. Hence, we describe the advantages and disadvantages of knockout techniques for circRNAs. In addition, we also put forward our thoughts regarding the mechanism and network of circRNAs to provide researchers with novel ideas of how molecular biology can help us advance our goals in animal farming. This article is categorized under: RNA in Disease and Development > RNA in Disease RNA Interactions with Proteins and Other Molecules > Protein-RNA Interactions: Functional Implications RNA Interactions with Proteins and Other Molecules > Protein-RNA Recognition RNA Interactions with Proteins and Other Molecules > RNA-Protein Complexes.

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来源期刊
CiteScore
14.80
自引率
4.10%
发文量
67
审稿时长
6-12 weeks
期刊介绍: WIREs RNA aims to provide comprehensive, up-to-date, and coherent coverage of this interesting and growing field, providing a framework for both RNA experts and interdisciplinary researchers to not only gain perspective in areas of RNA biology, but to generate new insights and applications as well. Major topics to be covered are: RNA Structure and Dynamics; RNA Evolution and Genomics; RNA-Based Catalysis; RNA Interactions with Proteins and Other Molecules; Translation; RNA Processing; RNA Export/Localization; RNA Turnover and Surveillance; Regulatory RNAs/RNAi/Riboswitches; RNA in Disease and Development; and RNA Methods.
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