Hongyun Wang , Shimin Yang , Jiejie Liu , Zhiying Fu , Yingle Liu , Li Zhou , Haitao Guo , Ke Lan , Yu Chen
{"title":"人类腺病毒：新冠肺炎大流行期间儿童急性肝炎爆发的幕后嫌疑人。","authors":"Hongyun Wang , Shimin Yang , Jiejie Liu , Zhiying Fu , Yingle Liu , Li Zhou , Haitao Guo , Ke Lan , Yu Chen","doi":"10.1016/j.cellin.2022.100043","DOIUrl":null,"url":null,"abstract":"<div><p>As of 10 May 2022, at least 450 cases of pediatric patients with acute hepatitis of unknown cause have been reported worldwide. Human adenoviruses (HAdVs) have been detected in at least 74 cases, including the F type HAdV41 in 18 cases, which indicates that adenoviruses may be associated with this mysterious childhood hepatitis, although other infectious agents or environmental factors cannot be excluded. In this review, we provide a brief introduction of the basic features of HAdVs and describe diseases caused by different HAdVs in humans, aiming to help understand the biology and potential risk of HAdVs and cope with the outbreak of acute child hepatitis.</p></div>","PeriodicalId":72541,"journal":{"name":"Cell insight","volume":"1 4","pages":"Article 100043"},"PeriodicalIF":0.0000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/c4/main.PMC10120317.pdf","citationCount":"3","resultStr":"{\"title\":\"Human adenoviruses: A suspect behind the outbreak of acute hepatitis in children amid the COVID-19 pandemic\",\"authors\":\"Hongyun Wang , Shimin Yang , Jiejie Liu , Zhiying Fu , Yingle Liu , Li Zhou , Haitao Guo , Ke Lan , Yu Chen\",\"doi\":\"10.1016/j.cellin.2022.100043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>As of 10 May 2022, at least 450 cases of pediatric patients with acute hepatitis of unknown cause have been reported worldwide. Human adenoviruses (HAdVs) have been detected in at least 74 cases, including the F type HAdV41 in 18 cases, which indicates that adenoviruses may be associated with this mysterious childhood hepatitis, although other infectious agents or environmental factors cannot be excluded. In this review, we provide a brief introduction of the basic features of HAdVs and describe diseases caused by different HAdVs in humans, aiming to help understand the biology and potential risk of HAdVs and cope with the outbreak of acute child hepatitis.</p></div>\",\"PeriodicalId\":72541,\"journal\":{\"name\":\"Cell insight\",\"volume\":\"1 4\",\"pages\":\"Article 100043\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/c4/main.PMC10120317.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell insight\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772892722000402\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell insight","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772892722000402","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Human adenoviruses: A suspect behind the outbreak of acute hepatitis in children amid the COVID-19 pandemic
As of 10 May 2022, at least 450 cases of pediatric patients with acute hepatitis of unknown cause have been reported worldwide. Human adenoviruses (HAdVs) have been detected in at least 74 cases, including the F type HAdV41 in 18 cases, which indicates that adenoviruses may be associated with this mysterious childhood hepatitis, although other infectious agents or environmental factors cannot be excluded. In this review, we provide a brief introduction of the basic features of HAdVs and describe diseases caused by different HAdVs in humans, aiming to help understand the biology and potential risk of HAdVs and cope with the outbreak of acute child hepatitis.
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