CAR - t细胞治疗中的实际问题。

IF 2.3 Q2 HEMATOLOGY
Ja Min Byun
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引用次数: 1

摘要

嵌合抗原受体(CAR) t细胞疗法在个性化癌症治疗方面取得了革命性的进展。在生产过程中,患者自身的t细胞通过基因工程来表达一种与肿瘤抗原结合的合成受体。然后将CAR - t细胞扩增用于临床,并注入患者体内以攻击癌细胞。尽管CAR - t细胞疗法被认为是癌症免疫治疗的重大突破,但它并非没有局限性。在这篇综述中,我们讨论了在韩国有效的CAR - t细胞治疗的障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Practical issues in CAR T-cell therapy.

Chimeric antigen receptor (CAR) T-cell therapy presents a revolutionary advancement in personalized cancer treatment. During the production process, the patient's own T-cells are genetically engineered to express a synthetic receptor that binds to a tumor antigen. CAR T-cells are then expanded for clinical use and infused back into the patient's body to attack cancer cells. Although CAR T-cell therapy is considered a major breakthrough in cancer immunotherapy, it is not without limitations. In this review, we discuss the barriers to effective CAR T-cell therapy in Korea.

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来源期刊
Blood Research
Blood Research HEMATOLOGY-
CiteScore
3.70
自引率
0.00%
发文量
64
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