组织间置皮瓣在膀胱阴道瘘修复中的应用综述。

IF 2.6 4区 医学 Q2 UROLOGY & NEPHROLOGY
Halime Serinçay, Hayrullah Uğur Güler, Kezban Ulubayram, Naşide Mangır
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引用次数: 0

摘要

背景:组织间置皮瓣(TIFs)在膀胱阴道瘘(VVF)修复中的应用是一个广泛的研究领域,其中天然和合成材料的应用范围非常广泛。在社会和临床环境中,VVF的发生也各不相同,导致其治疗的已发表文献也存在类似的异质性。由于缺乏最有效的TIF类型和技术,在VVF修复中使用合成和自体TIF尚未标准化。目的:本研究的目的是系统地回顾所有用于VVFs手术修复的人工合成和自体TIFs。资料来源和方法:在本综述中,确定了符合纳入标准的自体和合成间置皮瓣用于VVF治疗的手术结果。我们使用Ovid MEDLINE和PubMed数据库检索了1974年至2022年间的文献。记录研究特征,并由两位作者独立从每项研究中提取有关瘘管大小和位置变化、手术入路、成功率、术前患者评价和结局评价的数据。结果:符合纳入标准的文献共25篇纳入最终分析。共有943例和127例患者分别接受了自体皮瓣和合成皮瓣,纳入了本范围综述。瘘管的大小、复杂程度、病因、位置和放射程度各不相同。在纳入的研究中,对瘘管修复的结果评估主要基于症状评估。体检、膀胱造影和亚甲蓝试验是首选的检查方法。所有纳入的研究均报告了瘘口修复后患者的术后并发症,如感染、出血、供区、疼痛、排尿功能障碍等并发症。结论:TIFs在瘘管修复中应用较为普遍,尤其在复杂、大的瘘管中应用更为广泛。自体TIFs似乎是目前治疗的标准,合成TIFs在有限数量的选定病例的前瞻性临床试验中进行了研究。评估间置皮瓣有效性的临床研究证据水平总体较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A scoping review of tissue interposition flaps used in vesicovaginal fistulae repair.

A scoping review of tissue interposition flaps used in vesicovaginal fistulae repair.

A scoping review of tissue interposition flaps used in vesicovaginal fistulae repair.

A scoping review of tissue interposition flaps used in vesicovaginal fistulae repair.

Background: Research on the use of tissue interposition flaps (TIFs) in vesicovaginal fistulae (VVF) repair is a broad area where a very wide range of natural and synthetic materials have been used. The occurrence of VVF is also diverse in the social and clinical settings, resulting in a parallel heterogeneity in the published literature on its treatment. The use of synthetic and autologous TIFs in VVF repair is not yet standardized with a lack of the most efficacious type and technique of the TIF.

Objectives: The aim of this study was to systematically review all synthetic and autologous TIFs used in the surgical repair of VVFs.

Data sources and methods: In this scoping review, the surgical outcomes of autologous and synthetic interposition flaps used in VVF treatment meeting the inclusion criteria were determined. We searched the literature using Ovid MEDLINE and PubMed databases between 1974 and 2022. Study characteristics were recorded, and data on the change in fistulae size and location, surgical approach, success rate, preoperative patient evaluation and outcome evaluation were extracted from each study independently by two authors.

Results: A total of 25 articles that met the inclusion criteria were included in the final analysis. A total of 943 and 127 patients who had received autologous and synthetic flaps, respectively, were included in this scoping review. The fistulae characteristics were highly variable with regard to their size, complexity, aetiology, location and radiation. Outcome assessments of fistulae repair in included studies were mostly based on symptom evaluation. Physical examination, cystogram and methylene blue test were the methods in order of preference. Postoperative complications, such as infection, bleeding, donor site, pain, voiding dysfunction and other complications, were reported in patients after fistulae repair in all included studies.

Conclusion: The use of TIFs in VVF repair was common especially in complex and large fistulae. Autologous TIFs appear to be the standard of care at the moment, and synthetic TIFs were investigated in prospective clinical trials in a limited number of selected cases. Evidence levels of clinical studies evaluating the effectiveness of interposition flaps were overall low.

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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
39
审稿时长
10 weeks
期刊介绍: Therapeutic Advances in Urology delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of urology. The journal has a strong clinical and pharmacological focus and is aimed at clinicians and researchers in urology, providing a forum in print and online for publishing the highest quality articles in this area. The editors welcome articles of current interest across all areas of urology, including treatment of urological disorders, with a focus on emerging pharmacological therapies.
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