{"title":"新生儿重症监护室院内表皮葡萄球菌和鲍曼不动杆菌感染的流行病学。","authors":"Fatemeh Nayeri, Hosein Dalili, Mamak Shariat, Nahid Farrokhzad, Kosar Abouhamzeh, Leyla Sahebi","doi":"10.18502/ijm.v15i3.12895","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to investigate epidemiology of <i>Staphylococcus epidermidis (S. epidermidis)</i> and <i>Acinetobacter baumannii (A. baumannii)</i> infections in neonatal intensive care unit (NICU) in a period of 8 years.</p><p><strong>Materials and methods: </strong>This retrospective cohort study was conducted on 46 cases of nosocomial infection by <i>S. epidermidis,</i> and 44 neonates with <i>A. baumannii</i> in NICU of Valiasr hospital, Iran.</p><p><strong>Results: </strong>The trend of <i>A. baumannii</i> and <i>S. epidermidis</i> infection were as follows: 1 and 7 in 2014, 11 and 7 in 2015, 20 and 11 in 2016, 1 and 4 in 2017, 4 and 6 in 2018, 4 and 4 in 2019, 0 and 1 in 2020, and 3 and 6 in 2021-March 2022 respectively. Mortality proportion (%) in neonates with <i>S. epidermidis</i> and <i>A. baumannii</i> infection was at 8.3 and 32.1, respectively. There was a strong positive correlation between number of infected neonates in month and average of prescribed antibiotics before incidence of infection in every baby in that month. Fluconazole prescription before incidence of infection were associated with the <i>A. baumannii</i> infection in month too. Amikacin prescription had adjusted correlation on increasing of <i>A. baumannii</i> and <i>S. epidermidis</i> infection in month.</p><p><strong>Conclusion: </strong>It seems reducing of hospitalization duration and medication prescriptions management plays an important role in reducing of nosocomial infections.</p>","PeriodicalId":14633,"journal":{"name":"Iranian Journal of Microbiology","volume":"15 3","pages":"350-358"},"PeriodicalIF":1.3000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/b3/IJM-15-350.PMC10336283.pdf","citationCount":"0","resultStr":"{\"title\":\"Epidemiology of nosocomial <i>Staphylococcus epidermidis</i> and <i>Acinetobacter baumannii</i> infections in a neonatal intensive care unit.\",\"authors\":\"Fatemeh Nayeri, Hosein Dalili, Mamak Shariat, Nahid Farrokhzad, Kosar Abouhamzeh, Leyla Sahebi\",\"doi\":\"10.18502/ijm.v15i3.12895\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and objectives: </strong>This study aimed to investigate epidemiology of <i>Staphylococcus epidermidis (S. epidermidis)</i> and <i>Acinetobacter baumannii (A. baumannii)</i> infections in neonatal intensive care unit (NICU) in a period of 8 years.</p><p><strong>Materials and methods: </strong>This retrospective cohort study was conducted on 46 cases of nosocomial infection by <i>S. epidermidis,</i> and 44 neonates with <i>A. baumannii</i> in NICU of Valiasr hospital, Iran.</p><p><strong>Results: </strong>The trend of <i>A. baumannii</i> and <i>S. epidermidis</i> infection were as follows: 1 and 7 in 2014, 11 and 7 in 2015, 20 and 11 in 2016, 1 and 4 in 2017, 4 and 6 in 2018, 4 and 4 in 2019, 0 and 1 in 2020, and 3 and 6 in 2021-March 2022 respectively. Mortality proportion (%) in neonates with <i>S. epidermidis</i> and <i>A. baumannii</i> infection was at 8.3 and 32.1, respectively. There was a strong positive correlation between number of infected neonates in month and average of prescribed antibiotics before incidence of infection in every baby in that month. Fluconazole prescription before incidence of infection were associated with the <i>A. baumannii</i> infection in month too. Amikacin prescription had adjusted correlation on increasing of <i>A. baumannii</i> and <i>S. epidermidis</i> infection in month.</p><p><strong>Conclusion: </strong>It seems reducing of hospitalization duration and medication prescriptions management plays an important role in reducing of nosocomial infections.</p>\",\"PeriodicalId\":14633,\"journal\":{\"name\":\"Iranian Journal of Microbiology\",\"volume\":\"15 3\",\"pages\":\"350-358\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/b3/IJM-15-350.PMC10336283.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Iranian Journal of Microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18502/ijm.v15i3.12895\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/ijm.v15i3.12895","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit.
Background and objectives: This study aimed to investigate epidemiology of Staphylococcus epidermidis (S. epidermidis) and Acinetobacter baumannii (A. baumannii) infections in neonatal intensive care unit (NICU) in a period of 8 years.
Materials and methods: This retrospective cohort study was conducted on 46 cases of nosocomial infection by S. epidermidis, and 44 neonates with A. baumannii in NICU of Valiasr hospital, Iran.
Results: The trend of A. baumannii and S. epidermidis infection were as follows: 1 and 7 in 2014, 11 and 7 in 2015, 20 and 11 in 2016, 1 and 4 in 2017, 4 and 6 in 2018, 4 and 4 in 2019, 0 and 1 in 2020, and 3 and 6 in 2021-March 2022 respectively. Mortality proportion (%) in neonates with S. epidermidis and A. baumannii infection was at 8.3 and 32.1, respectively. There was a strong positive correlation between number of infected neonates in month and average of prescribed antibiotics before incidence of infection in every baby in that month. Fluconazole prescription before incidence of infection were associated with the A. baumannii infection in month too. Amikacin prescription had adjusted correlation on increasing of A. baumannii and S. epidermidis infection in month.
Conclusion: It seems reducing of hospitalization duration and medication prescriptions management plays an important role in reducing of nosocomial infections.
期刊介绍：
The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.
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