Marco Brusasco, Claudio Feliciani, Maria Beatrice de Felici Del Giudice
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A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an altered innate immunity with an increased risk of potentially lethal bacterial and fungal infections. Although chronic granulomatous disease is rare, acne is a common manifestation in these patients, but there are no data about the gold standard therapy.
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