非青光眼黄斑水肿患者玻璃体内注射阿瓦斯丁后平均眼压变化。

Q3 Medicine
Adila Anwar, Ayyaz Hussain Awan, Anjum Imdad, Sufian Ali Khan, Mutahir Shah, Misbah Naeem
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引用次数: 0

摘要

背景:视网膜层之间的液体积聚称为视网膜或黄斑水肿,而视网膜内水肿或黄斑水肿是指直接在视网膜内积聚液体。该研究的目的是评估玻璃体内注射贝伐单抗对非青光眼黄斑水肿患者眼压(IOP)的影响。方法:行介入前后研究。采用非概率连续抽样方法对220例患者进行了研究。采用Open Epi软件确定样本量。伊斯兰堡三级保健医院眼科主持了这项为期六个月的研究。结果:研究参与者年龄30 ~ 60岁,平均年龄50.38±6.53岁。220例患者男女比例为1:6 .6,其中男性86例(39.09%),女性134例(60.91%)。基线时平均IOP为11.57±1.42 mmHg,注射后1个月平均IOP为12.81±1.18 mmHg,平均IOP变化1.24±0.87 mmHg。结论:本研究发现,非青光眼黄斑水肿患者在玻璃体内注射阿瓦斯汀后,眼压(IOP)的平均变化较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mean Iop Change In Non-Glaucomatous Patients With Macular Edema Subsequently Intravitreal Injection Avastin.

Background: The accumulation of fluid between the retinal layers is called retinal or macular oedema, while intraretinal oedema, or macular oedema, refers to fluid accumulation directly within the retina. The purpose of the study was to evaluate the effects of intravitreal injections of bevacizumab on intraocular pressure (IOP) in Non-Glaucomatous patients with Macular Oedema.

Methods: A pre-and post-interventional study was conducted. 220 patients were studied utilizing a non-probability, consecutive sampling method. Open Epi software was used to determine the sample size. The Department of Ophthalmology at Islamabad's Tertiary Care Hospital hosted the study, which lasted six months.

Results: The study's participants ranged in age from 30 to 60, with a mean age of 50.38±6.53 years. Male to female ratio of these 220 patients was 1:1.6, with 86 (39.09%) men and 134 (60.91%) women. The mean IOP at baseline was 11.57±1.42 mmHg, and the mean IOP one month after the injection was 12.81±1.18 mmHg, with a mean change in IOP of 1.24±0.87 mmHg.

Conclusions: This study found that non-glaucomatous patients with macular oedema experienced a high mean change in intraocular pressure (IOP) after intravitreal Avastin.

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CiteScore
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