甲状腺功能减退和低钠血症之间是否存在因果关系?

IF 3.9 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Therapeutic Advances in Endocrinology and Metabolism Pub Date : 2023-01-01 DOI:10.1177/20420188231180983

Julie Chen

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引用次数: 0

摘要

低钠血症是临床上最常见的实验室异常之一。甲状腺功能减退症是低血容量性低钠血症的病因，这一观点已被广泛接受。其主要机制被认为是由于游离水排泄受损和肾脏中钠处理的变化。然而，临床研究是相互矛盾的，并没有明确证实甲状腺功能减退和低钠血症之间的联系。因此，如果没有黏液性水肿昏迷的患者出现严重低钠血症，则应寻找其他潜在的病因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Is there a causal relationship between hypothyroidism and hyponatremia?

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Is there a causal relationship between hypothyroidism and hyponatremia?

Hyponatremia is one of the most common lab abnormalities seen in clinical practice. It has become widely accepted that hypothyroidism is a cause of euvolemic hyponatremia. The primary mechanism is thought to be due to impaired free water excretion and changes in sodium handling in the kidney. However, the clinical studies are conflicting and do not definitively confirm the association between hypothyroidism and hyponatremia. Therefore, if severe hyponatremia occurs in a patient without myxedema coma, other potential etiologies should be sought.

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来源期刊

Therapeutic Advances in Endocrinology and Metabolism Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

7.70

自引率

2.60%

发文量

审稿时长

8 weeks

期刊介绍： Therapeutic Advances in Endocrinology and Metabolism delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of endocrinology and metabolism.