用作辅助手术工具的聚合物纳米材料。

IF 6.9 2区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
Metecan Erdi, Anthony Sandler, Peter Kofinas
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引用次数: 0

摘要

用于治疗外科和临床实践中遇到的疾病的材料在转化为应用方面经常面临障碍。缺点可以通过其机械稳定性降低、处理困难以及无法顺应或粘附于复杂组织表面来概括。为了克服各种挑战,研究人员寻求利用以各种方式和配方沉积的聚合物衍生纳米材料,以改善手术和临床干预的应用和结果。临床上流行的应用包括局部伤口敷料、组织粘合剂、外科密封剂、止血剂和粘附屏障,所有这些都显示出作为当前外科手术中使用的材料的优越替代品的潜力。在这篇综述中,重点不仅放在应用上,还放在制造中采用的各种设计策略上。这篇综述旨在对纳米材料作为辅助治疗手术中普遍存在的病理学的辅助工具提供广泛而发人深省的理解。本文分类如下:植入材料和外科技术>纳米材料和植入物植入材料和手术技术>外科中的纳米工具和技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Polymer nanomaterials for use as adjuvant surgical tools.

Polymer nanomaterials for use as adjuvant surgical tools.

Materials employed in the treatment of conditions encountered in surgical and clinical practice frequently face barriers in translation to application. Shortcomings can be generalized through their reduced mechanical stability, difficulty in handling, and inability to conform or adhere to complex tissue surfaces. To overcome an amalgam of challenges, research has sought the utilization of polymer-derived nanomaterials deposited in various fashions and formulations to improve the application and outcomes of surgical and clinical interventions. Clinically prevalent applications include topical wound dressings, tissue adhesives, surgical sealants, hemostats, and adhesion barriers, all of which have displayed the potential to act as superior alternatives to current materials used in surgical procedures. In this review, emphasis will be placed not only on applications, but also on various design strategies employed in fabrication. This review is designed to provide a broad and thought-provoking understanding of nanomaterials as adjuvant tools for the assisted treatment of pathologies prevalent in surgery. This article is categorized under: Implantable Materials and Surgical Technologies > Nanomaterials and Implants Implantable Materials and Surgical Technologies > Nanoscale Tools and Techniques in Surgery.

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来源期刊
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology NANOSCIENCE & NANOTECHNOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL
CiteScore
16.60
自引率
2.30%
发文量
93
期刊介绍: Nanotechnology stands as one of the pivotal scientific domains of the twenty-first century, recognized universally for its transformative potential. Within the biomedical realm, nanotechnology finds crucial applications in nanobiotechnology and nanomedicine, highlighted as one of seven emerging research areas under the NIH Roadmap for Medical Research. The advancement of this field hinges upon collaborative efforts across diverse disciplines, including clinicians, biomedical engineers, materials scientists, applied physicists, and toxicologists. Recognizing the imperative for a high-caliber interdisciplinary review platform, WIREs Nanomedicine and Nanobiotechnology emerges to fulfill this critical need. Our topical coverage spans a wide spectrum, encompassing areas such as toxicology and regulatory issues, implantable materials and surgical technologies, diagnostic tools, nanotechnology approaches to biology, therapeutic approaches and drug discovery, and biology-inspired nanomaterials. Join us in exploring the frontiers of nanotechnology and its profound impact on biomedical research and healthcare.
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