基因编辑猪肾移植临床试验患者知情同意书:一份代表性同意书。

IF 3.3 4区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

Xenotransplantation Pub Date : 2023-01-01 DOI:10.1111/xen.12790

David K C Cooper

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引用次数: 2

摘要

当开展基因编辑猪器官移植临床试验时，要求患者签署的同意书将是一份重要文件。同意接受猪异种移植与大多数实验性临床程序的要求有很大的不同。在此，我们建议制定一份猪肾移植同意书，说明需要的要点，并希望它能为讨论和未来必要时的修改提供基础。文件中故意有一些重复，但我们认为这是必要的，以确保患者清楚地了解他/她同意的内容。

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Patient informed consent for a clinical trial of gene-edited pig kidney transplantation: A representative consent form.

When clinical trials of gene-edited pig organ transplantation are initiated, the consent form that the patient is requested to sign will be an important document. Consent to receive a pig xenograft will have significant differences when compared with the requirements of most experimental clinical procedures. We here suggest a consent form for pig kidney transplantation that addresses the major points that will be required and hope it will provide a basis for discussion and future modification, if necessary. There is purposely some repetition in the document, but we believe this is necessary to ensure that the patient has a clear understanding of what he/she is consenting to.

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来源期刊

Xenotransplantation 医学-医学：研究与实验

CiteScore

6.80

自引率

15.40%

发文量

审稿时长

>12 weeks

期刊介绍： Xenotransplantation provides its readership with rapid communication of new findings in the field of organ and tissue transplantation across species barriers.The journal is not only of interest to those whose primary area is xenotransplantation, but also to veterinarians, microbiologists and geneticists. It also investigates and reports on the controversial theological, ethical, legal and psychological implications of xenotransplantation.