后巩膜炎的脉络膜上曲安奈德注射:病例报告。

IF 2.6 4区 医学 Q2 OPHTHALMOLOGY
Ocular Immunology and Inflammation Pub Date : 2024-09-01 Epub Date: 2023-07-14 DOI:10.1080/09273948.2023.2232447
Ploysai Rujkorakarn, Avery Zhou, Fatima Babiker, Peter Y Chang
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引用次数: 0

摘要

脉络膜上曲安奈德(SCS-TA)注射最近被批准用于治疗非感染性葡萄膜炎继发的黄斑水肿。然而,将其用于治疗后巩膜炎的报道却寥寥无几。我们报告了首例使用 SCS-TA 治疗后巩膜炎的病例。一名 67 岁的妇女患有后巩膜炎,并发渗出性视网膜脱离,经光谱域光学相干断层扫描(OCT)确诊。此前,医生曾给她开过泼尼松龙外用药和口服泼尼松,但效果甚微。她还患有类风湿性关节炎,曾接受过多种系统性免疫抑制剂治疗。接受 SCS-TA 治疗后,患者的疼痛缓解,视力也有所提高。OCT 显示巩膜脉络膜增厚明显减轻。通过其新颖的给药方法,SCS-TA 可能是治疗后巩膜炎的有效方法。要确定这种治疗方式的长期疗效和安全性,还需要进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Suprachoroidal Triamcinolone Injection in Posterior Scleritis: A Case Report.

Suprachoroidal triamcinolone acetonide (SCS-TA) injections were recently approved to treat macular edema secondary to noninfectious uveitis. However, its use in managing posterior scleritis has not been reported. We report the first case of SCS-TA used in the treatment of posterior scleritis. A 67-year-old woman with posterior scleritis complicated by exudative retinal detachment, diagnosed by spectral-domain optical coherence tomography scan (OCT), presented with pain, decreased vision, and redness in the left eye for 8 months. She was previously prescribed topical prednisolone and oral prednisone with minimal improvement. She also had a history of rheumatoid arthritis treated with multiple systemic immunosuppressive agents. After SCS-TA, the patient's pain resolved and visual acuity improved. OCT demonstrated significant reduction in sclerochoroidal thickening. Via its novel delivery method, SCS-TA may be an effective treatment for posterior scleritis. Further studies are needed to establish long-term efficacy and safety of this treatment modality.

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来源期刊
CiteScore
6.20
自引率
15.20%
发文量
285
审稿时长
6-12 weeks
期刊介绍: Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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