颗粒细胞亚群及其在宿主对结核分枝杆菌耐药性中的不同功能——疾病恶化的“临界点”模型。

IF 6.6 2区医学 Q1 IMMUNOLOGY

Current Opinion in Immunology Pub Date : 2023-10-01 DOI:10.1016/j.coi.2023.102365

Katrin D Mayer-Barber

引用次数: 1

摘要

颗粒细胞是先天免疫效应细胞，在宿主抵抗细菌感染方面具有重要功能。我将讨论新出现的证据，即在结核分枝杆菌感染期间，与直觉相反，嗜酸性粒细胞对宿主具有保护作用，而中性粒细胞则对宿主有害。此外，我将提出一个“临界点”模型，其中中性粒细胞是驱动结核病恶化的前馈回路的组成部分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Granulocytes subsets and their divergent functions in host resistance to Mycobacterium tuberculosis — a ‘tipping-point’ model of disease exacerbation

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来源期刊

Current Opinion in Immunology 医学-免疫学

CiteScore

13.30

自引率

1.40%

发文量

审稿时长

67 days

期刊介绍： Current Opinion in Immunology aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed. In Current Opinion in Immunology we help the reader by providing in a systematic manner: 1. The views of experts on current advances in their field in a clear and readable form. 2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications. Current Opinion in Immunology will serve as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students. Current Opinion in Immunology builds on Elsevier''s reputation for excellence in scientific publishing and long-standing commitment to communicating reproducible biomedical research targeted at improving human health. It is a companion to the new Gold Open Access journal Current Research in Immunology and is part of the Current Opinion and Research(CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy-of editorial excellence, high-impact, and global reach-to ensure they are a widely read resource that is integral to scientists'' workflow.