干细胞与先天性心脏病：当前治疗之外的未来潜在临床治疗。

IF 2.4 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Cardiology Reviews Pub Date : 2023-01-01 DOI:10.2174/1573403X18666220531093326

Katherine Julian, Nikita Garg, Narutoshi Hibino, Rohit Jain

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引用次数: 0

摘要

先天性心脏病（CHD）是新生儿最常见的先天性畸形。目前紫绀型冠心病的治疗在很大程度上依赖于手术干预；然而，CHD患者的发病率和死亡率仍然很高。最近探索治疗冠心病新途径的研究包括干细胞在该领域的应用。干细胞已经被用于建模和潜在的治疗CHD。迄今为止，大多数临床应用都集中在左心发育不全综合征上。在这里，我们研究了干细胞在冠心病中的当前作用，并讨论了该领域的未来应用。

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Stem Cells and Congenital Heart Disease: The Future Potential Clinical Therapy Beyond Current Treatment.

Congenital heart disease (CHD) is the most common congenital anomaly in newborns. Current treatment for cyanotic CHD largely relies on the surgical intervention; however, significant morbidity and mortality for patients with CHD remain. Recent research to explore new avenues of treating CHD includes the utility of stem cells within the field. Stem cells have since been used to both model and potentially treat CHD. Most clinical applications to date have focused on hypoplastic left heart syndrome. Here, we examine the current role of stem cells in CHD and discuss future applications within the field.

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来源期刊

Current Cardiology Reviews CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

3.70

自引率

10.50%

发文量

117

期刊介绍： Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.