假牙感染的植物药物治疗。

Q3 Pharmacology, Toxicology and Pharmaceutics
K V Anitha, Rajkumar K
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引用次数: 0

摘要

天然牙齿是咀嚼系统的一个组成部分。缺牙会损害患者的口腔功能、面部外观和语音。修复义齿是恢复口腔形态和咀嚼活动的必要手段。目前,可移动和固定假体的制造已经成为最可预测的。尽管如此,多年来在佩戴活动义齿的无牙个体中观察到的口腔炎患病率有所增加。在引起假牙感染的许多病原体中,白色念珠菌被认为是最致命的机会性病原体。不同的方法,如机械,化学,化学机械和药理学试图对抗这种感染。尽管有各种治疗假牙口炎的策略,但研究仍在不断发展出最优的一种。口腔和(或)义齿卫生维护不当、义齿表面不规则、口干持续存在以及相关的全身性疾病构成疾病夸大的风险。在极端情况下,老年患者发生吸入性肺炎被认为是对牙科和医学专家的威胁。迄今为止,合成抗微生物药物的治疗管理以及细致的口腔卫生维护是推荐的方案。然而,诸如抗生素耐药性、副作用、药物反反应、药物成本等限制因素使天然草药产品无法用于治疗假牙口炎。在以前的文献中研究了大量的植物产品,但没有证明一种产品优于另一种产品的明确优势。本文就用于治疗念珠菌相关性假牙口炎(CADS)的不同有机植物材料(也称为植物药)作一综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management of Denture Infection with Phytomedicine.

Natural teeth are an integral part of the masticatory system. Absence of dentition subjects the individual to compromised oral function, facial appearance and phonetics. Rehabilitation with dental prosthesis is imperative to restore form and masticatory activity. Currently, fabrication of removable and fixed prosthesis has become most predictable. Nonetheless, there is an increased prevalence of oral stomatitis observed over the years in edentulous individuals wearing removable dentures. Amongst the many pathogens that cause denture infections, Candida albicans is assumed to be the most virulent opportunistic agent. Different methods, such as mechanical, chemical, chemicmechanical, and pharmacological are tried to fight such infections. Regardless of various management strategies developed to treat denture stomatitis, the research continues to evolve the most optimal one. Improper oral and or denture hygiene maintenance, surface irregularities on denture, persistence of xerostomia and associated systemic illness pose risk for exaggeration of the disease. In extreme conditions, the development of aspiration pneumonia in geriatric patients is considered a threat to both dental and medical specialists. Therapeutic administration of synthetic anti-microbial drugs, along with meticulous oral hygiene maintenance are recommended protocols till date. However, limitations such as antibiotic resistance, side effects, counter drug reactions, cost of the medicaments predispose to origin of natural herbal products to treat denture stomatitis. Vast array of plant products are studied in previous literature, yet no definitive edge of one over the other is proven. This article intends to provide a mini-review on the different organic plant materials, also called as phytomedicines used for the treatment of candida associated denture stomatitis (CADS).

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来源期刊
Infectious disorders drug targets
Infectious disorders drug targets Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
3.10
自引率
0.00%
发文量
123
期刊介绍: Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continues to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.
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