日本成人 2 型糖尿病患者的心血管疾病患病率：CAPTURE 研究日本中心的结果。

IF 1.3 Q4 ENDOCRINOLOGY & METABOLISM

Diabetology International Pub Date : 2023-01-14 eCollection Date: 2023-04-01 DOI:10.1007/s13340-022-00612-y

Hiroaki Seino, Yukiko Onishi, Kosei Eguchi, Keiji Nishijima, Toshihiro Sato, Shinichiro Shirabe

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引用次数: 0

摘要

简介CAPTURE 是一项横断面、非干预性研究（NCT03786406、NCT03811288），调查了全球 13 个国家的 2 型糖尿病（T2D）成人心血管疾病（CVD）的患病率和特征。在此，我们介绍日本的调查结果：收集的数据来自2019年在诊所或医院接受治疗的年龄≥20岁（日本以外的国家年龄≥18岁）的成人2型糖尿病患者。所有国家均采用标准化方法。根据护理环境（诊所与医院）加权估算心血管疾病及其亚型的患病率：在日本的参与者（总计：800 人；诊所：440 人；医院：360 人）中，平均（标准差）年龄为 65.6 (11.2) 岁，糖化血红蛋白为 7.2% (0.9)。67%的参与者为男性，57.8%的参与者糖尿病病程超过 10 年，49.8%的参与者体重指数≥ 25 kg/m2，63.1%的参与者患有高血压。心血管疾病和动脉粥样硬化性心血管疾病的加权患病率（95% 置信区间 [CI]）分别为 37.3% (34.2;40.3) 和 33.5% (30.6;36.4)。最常见的心血管疾病亚型的患病率（95% CI）分别为：颈动脉疾病 20.5% (18.2;22.8)、冠心病 11.9% (9.7;14.1)和脑血管疾病 10.4% (8.3;12.5)：这些来自日本 T2D 成人心血管疾病患病率 CAPTURE 研究的当代数据显示，大约每三名 T2D 成人中就有一人已确诊为心血管疾病，这与全球研究队列中的患病率相当：在线版本包含补充材料，可在 10.1007/s13340-022-00612-y.上查阅。

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Cardiovascular disease prevalence in adults with type 2 diabetes in Japan: results from the Japanese centers in the CAPTURE study.

Introduction: CAPTURE was a cross-sectional, non-interventional study (NCT03786406, NCT03811288) investigating the prevalence and characteristics of cardiovascular disease (CVD) in adults with type 2 diabetes (T2D) across 13 countries worldwide. Here we present the findings for Japan.

Materials and methods: Data were collected from adults aged ≥ 20 years (aged ≥ 18 years in countries outside Japan) with T2D who were managed in clinics or hospitals in 2019. Standardized methodology was used for all countries. The prevalence of CVD and its subtypes was estimated, weighted by care setting (clinics versus hospitals).

Results: Among participants from Japan (total: 800; clinics: 440; hospitals: 360), mean (standard deviation) age was 65.6 (11.2) years and glycated hemoglobin 7.2% (0.9). Sixty-seven percent of participants were male, 57.8% had diabetes duration > 10 years, 49.8% had body mass index ≥ 25 kg/m² and 63.1% had hypertension. The weighted prevalences (95% confidence interval [CI]) of CVD and atherosclerotic CVD were 37.3% (34.2;40.3) and 33.5% (30.6;36.4), respectively. The prevalence (95% CI) of the most common subtypes of CVD was: carotid artery disease 20.5% (18.2;22.8), coronary heart disease 11.9% (9.7;14.1) and cerebrovascular disease 10.4% (8.3;12.5).

Conclusions: These contemporary data from the CAPTURE study on CVD prevalence in adults with T2D in Japan show that approximately one in three adults with T2D had established CVD, which is comparable to the prevalence in the global study cohort.

Supplementary information: The online version contains supplementary material available at 10.1007/s13340-022-00612-y.

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来源期刊

Diabetology International ENDOCRINOLOGY & METABOLISM-

CiteScore

3.90

自引率

4.50%

发文量

期刊介绍： Diabetology International, the official journal of the Japan Diabetes Society, publishes original research articles about experimental research and clinical studies in diabetes and related areas. The journal also presents editorials, reviews, commentaries, reports of expert committees, and case reports on any aspect of diabetes. Diabetology International welcomes submissions from researchers, clinicians, and health professionals throughout the world who are interested in research, treatment, and care of patients with diabetes. All manuscripts are peer-reviewed to assure that high-quality information in the field of diabetes is made available to readers. Manuscripts are reviewed with due respect for the author''s confidentiality. At the same time, reviewers also have rights to confidentiality, which are respected by the editors. The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.