《重度贫血:精神分裂症复发罕见诱因1例》。

IF 2.1 Q3 HEMATOLOGY

Journal of Blood Medicine Pub Date : 2023-01-01 DOI:10.2147/JBM.S407722

Krittisak Anuroj, Siwat Chongbanyatcharoen, Romteera Chiencharoenthanakij

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引用次数: 1

摘要

一例48岁的稳定残余精神分裂症患者，在发生严重的联合免疫溶血和纯红细胞再生障碍性贫血后，出现综合征性精神病复发，血红蛋白水平为4.7 g/dl。贫血的原因是她服用了抗艾滋病毒药物齐多夫定。她的艾滋病毒感染得到了很好的控制;未发现该精神病的其他器质性诱因。在输注2单位缺乏白细胞的红细胞后，精神分裂症症状迅速恢复到基线。这在3个月和6个月的随访中保持不变，不需要调整抗精神病药物的剂量。在停用齐多夫定和短期口服强的松龙后，她的贫血逐渐恢复。

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"Severe Anemia: A Case Report of an Uncommon Precipitant of Schizophrenia Relapse".

A 48-year-old patient with stable residual schizophrenia experienced a syndromic psychosis relapse following an episode of severe combined immunohemolytic and pure red cell aplastic anemia, with a hemoglobin level of 4.7 g/dl. The anemia was attributed to her anti-HIV medication zidovudine. Her HIV infection had been well-controlled; no other organic precipitant of the psychosis was found. Following transfusion of 2 units of leukocyte-poor packed red cells, schizophrenia symptoms promptly recovered to her baseline. This was maintained at 3- and 6-month follow-ups without any need for antipsychotic dose adjustment. Following zidovudine discontinuation and a short course of oral prednisolone, her anemia gradually recovered.

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来源期刊

Journal of Blood Medicine HEMATOLOGY-

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

16 weeks

期刊介绍： The Journal of Blood Medicine is an international, peer-reviewed, open access, online journal publishing laboratory, experimental and clinical aspects of all topics pertaining to blood based medicine including but not limited to: Transfusion Medicine (blood components, stem cell transplantation, apheresis, gene based therapeutics), Blood collection, Donor issues, Transmittable diseases, and Blood banking logistics, Immunohematology, Artificial and alternative blood based therapeutics, Hematology including disorders/pathology related to leukocytes/immunology, red cells, platelets and hemostasis, Biotechnology/nanotechnology of blood related medicine, Legal aspects of blood medicine, Historical perspectives. Original research, short reports, reviews, case reports and commentaries are invited.