{"title":"羧甲基壳聚糖无定形磷酸钙对原牙釉质表面硬度的浓度依赖性研究。","authors":"Theodora Elien, Heriandi Sutadi, Margaretha Suharsini","doi":"10.2334/josnusd.23-0084","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To compare the effects of gels containing 2.5% and 5% carboxymethyl chitosan amorphous calcium phosphate (CMC-ACP) on the microhardness of primary tooth enamel.</p><p><strong>Methods: </strong>Twenty-four tooth specimens were demineralized with 37% phosphoric acid and divided into four groups: an untreated control group, a positive control group treated with casein phosphopeptide amorphous calcium phosphate, and two groups treated with 2.5% and 5% CMC-ACP gel, respectively. The enamel surface hardness was then measured with a Vickers hardness tester.</p><p><strong>Results: </strong>In terms of Vickers Hardness Number (VHN), the degree of alteration in tooth surface microhardness was 77.83 ± 13.44 in the 5% CMC-ACP group and 52 ± 6.93 in the 2.5% CMC-ACP group (P = 0.002). The inter-group difference in the surface hardness change was significant (P < 0.05).</p><p><strong>Conclusion: </strong>The 5% CMC-ACP gel increased the hardness of primary tooth enamel to a greater degree than the 2.5% CMC-ACP gel.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Concentration-dependent effect of carboxymethyl chitosan amorphous calcium phosphate on the surface hardness of primary tooth enamel.\",\"authors\":\"Theodora Elien, Heriandi Sutadi, Margaretha Suharsini\",\"doi\":\"10.2334/josnusd.23-0084\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To compare the effects of gels containing 2.5% and 5% carboxymethyl chitosan amorphous calcium phosphate (CMC-ACP) on the microhardness of primary tooth enamel.</p><p><strong>Methods: </strong>Twenty-four tooth specimens were demineralized with 37% phosphoric acid and divided into four groups: an untreated control group, a positive control group treated with casein phosphopeptide amorphous calcium phosphate, and two groups treated with 2.5% and 5% CMC-ACP gel, respectively. The enamel surface hardness was then measured with a Vickers hardness tester.</p><p><strong>Results: </strong>In terms of Vickers Hardness Number (VHN), the degree of alteration in tooth surface microhardness was 77.83 ± 13.44 in the 5% CMC-ACP group and 52 ± 6.93 in the 2.5% CMC-ACP group (P = 0.002). The inter-group difference in the surface hardness change was significant (P < 0.05).</p><p><strong>Conclusion: </strong>The 5% CMC-ACP gel increased the hardness of primary tooth enamel to a greater degree than the 2.5% CMC-ACP gel.</p>\",\"PeriodicalId\":16646,\"journal\":{\"name\":\"Journal of oral science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of oral science\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.2334/josnusd.23-0084\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of oral science","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.2334/josnusd.23-0084","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Concentration-dependent effect of carboxymethyl chitosan amorphous calcium phosphate on the surface hardness of primary tooth enamel.
Purpose: To compare the effects of gels containing 2.5% and 5% carboxymethyl chitosan amorphous calcium phosphate (CMC-ACP) on the microhardness of primary tooth enamel.
Methods: Twenty-four tooth specimens were demineralized with 37% phosphoric acid and divided into four groups: an untreated control group, a positive control group treated with casein phosphopeptide amorphous calcium phosphate, and two groups treated with 2.5% and 5% CMC-ACP gel, respectively. The enamel surface hardness was then measured with a Vickers hardness tester.
Results: In terms of Vickers Hardness Number (VHN), the degree of alteration in tooth surface microhardness was 77.83 ± 13.44 in the 5% CMC-ACP group and 52 ± 6.93 in the 2.5% CMC-ACP group (P = 0.002). The inter-group difference in the surface hardness change was significant (P < 0.05).
Conclusion: The 5% CMC-ACP gel increased the hardness of primary tooth enamel to a greater degree than the 2.5% CMC-ACP gel.