单次白蛋白透析治疗新冠肺炎急性慢性肝功能衰竭报告1例]。

IF 0.5 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Gonzalo Ramírez-Guerrero, Anita Zurita-Poza, Romyna Baghetti-Hernández, Francisco Villagrán-Cortés, Bárbara Segovia-Hernández, Lisette Aguirre-Adones, Osvaldo Garay
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引用次数: 0

摘要

肝移植是唯一有效的治疗方法,以降低与急性肝衰竭和急性或慢性肝衰竭(ACLF)相关的高死亡率。单次白蛋白透析(SPAD)是一种体外支持治疗,用作肝移植或再生的桥梁。我们报告一名44岁的酒精性肝硬化男性,因COVID-19肺炎发展为ACLF而入院。SPAD技术完成了六个疗程,胆红素和氨水平降低。他发展为严重呼吸衰竭和难治性感染性休克,死亡。SPAD是一种安全有效的技术,旨在消除肝脏毒素,防止多器官损伤中断被称为“自中毒假说”的过程。它很容易在任何危重病人病房实施,并且比其他体外肝支持疗法成本更低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Single-pass albumin dialysis as treatment of acute on chronic liver failure during COVID-19 pneumonia. report of one case].

Liver transplantation is the only effective therapy to reduce the high mortality associated with acute liver failure and acute on chronic liver failure (ACLF). Single-pass albumin dialysis (SPAD) is an extracorporeal supportive therapy used as a bridge to liver transplantation or regeneration. We report a 44-year-old man with alcoholic cirrhosis admitted for critical COVID-19 pneumonia that evolves with ACLF. SPAD technique was performed completing six sessions, with a reduction of bilirubin and ammonia levels. He evolved with severe respiratory failure and refractory septic shock, dying. SPAD is a safe and efficient technique aimed to eliminate liver toxins, preventing multiorgan damage interrupting the process known as the "autointoxication hypothesis". It is easy to implement in any critical patient unit and has lower costs than other extracorporeal liver support therapies.

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来源期刊
Revista medica de Chile
Revista medica de Chile 医学-医学:内科
CiteScore
1.20
自引率
16.70%
发文量
75
审稿时长
3-6 weeks
期刊介绍: La Revista Médica de Chile publica trabajos originales sobre temas de interés médico y de Ciencias Biomédicas, dando preferencia a los relacionados con la Medicina Interna y sus especialidades derivadas. Publicada mensualmente, desde 1872, por la Sociedad Médica de Santiago. La abreviatura de su título es Rev Med Chile, que debe ser usado en bibliografías, notas al pié de página, leyendas y referencias bibliográficas.
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