石斛钟摆内酯衍生物的结构解析

IF 1.9 3区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Magnetic Resonance in Chemistry Pub Date : 2023-05-25 DOI:10.1002/mrc.5370

Mao-Sheng Zhang, Yu Jiang, Lei Cheng, Jian-Wen Yang, Min-Jian Dong, Cheng-Xin Sun, Shi-Ji Xiao

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引用次数: 0

摘要

从石斛钟摆中分离到6个内酯衍生物，包括4个α-吡酮衍生物(1-4)和2个α-呋喃酮衍生物(5和6)。这些未描述的内酯衍生物在详细的核磁共振分析的基础上完成了结构解析，化合物1-4的绝对构型通过电子圆二色性(ECD)技术得到了证实。采用MTT法评价了分离化合物对人乳腺癌细胞MDA-MB-231的细胞毒作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Structural elucidation of lactone derivatives from Dendrobium pendulum

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Structural elucidation of lactone derivatives from Dendrobium pendulum

Six lactone derivatives, including four α-pyrones derivatives (1–4), two α-furanone derivatives (5 and 6), were isolated from the Dendrobium pendulum. Structural elucidation of these undescribed lactone derivatives were accomplished on the basis of detailed nuclear magnetic resonance analysis, and the absolute configurations of compounds 1–4 were confirmed by electronic circular dichroism (ECD) techniques. The cytotoxic effects of isolated compounds on human breast cancer cell MDA-MB-231 were evaluated by the MTT assay.

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来源期刊

Magnetic Resonance in Chemistry 化学-光谱学

CiteScore

4.70

自引率

10.00%

发文量

审稿时长

1 months

期刊介绍： MRC is devoted to the rapid publication of papers which are concerned with the development of magnetic resonance techniques, or in which the application of such techniques plays a pivotal part. Contributions from scientists working in all areas of NMR, ESR and NQR are invited, and papers describing applications in all branches of chemistry, structural biology and materials chemistry are published. The journal is of particular interest not only to scientists working in academic research, but also those working in commercial organisations who need to keep up-to-date with the latest practical applications of magnetic resonance techniques.