高尿酸血症对甲状腺疾病影响的性别差异。

IF 1.5 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Endocrine Research Pub Date : 2023-10-02 Epub Date: 2023-06-29 DOI:10.1080/07435800.2023.2231092

Qiang Wang, Xixuan Lu, Li Xu, Haiyan Liang

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引用次数: 0

摘要

本研究旨在研究高尿酸血症对各种甲状腺疾病的影响，重点关注不同性别引起的差异。16094名年龄≥18岁的成年人这项横断面研究采用了随机分层抽样策略。测量了包括甲状腺功能和抗体、尿酸和人体测量在内的临床数据。多变量逻辑回归用于确定高尿酸血症与甲状腺疾病之间的相关性。患有高尿酸血症的女性患甲状腺功能亢进症的风险显著增加。高尿酸血症可能会显著增加女性患甲状腺功能亢进症和Graves病的风险。患有高尿酸血症的男性患甲状腺疾病的几率没有显著差异。

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Gender variations in the impact of hyperuricemia on thyroid disorders.

This study aimed to examine the impact of hyperuricemia on various thyroid disorders with emphasized focus on differences resulting from different genders. 16094 adults aged ≥18 years were enrolled in this cross-sectional study using a randomized stratified sampling strategy. Clinical data including thyroid function and antibodies, uric acid, and anthropometric measurements were measured. Multivariable logistic regression was used to determine the association between hyperuricemia and thyroid disorders. Women who have hyperuricemia are at a significantly increased risk of developing hyperthyroidism. Women's risk of overt hyperthyroidism and Graves' disease may be markedly increased by hyperuricemia. Men with hyperuricemia did not differ significantly in their chance of acquiring any thyroid disorders.

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来源期刊

Endocrine Research 医学-内分泌学与代谢

CiteScore

4.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： This journal publishes original articles relating to endocrinology in the broadest context. Subjects of interest include: receptors and mechanism of action of hormones, methodological advances in the detection and measurement of hormones; structure and chemical properties of hormones. Invitations to submit Brief Reviews are issued to specific authors by the Editors.