David Pezoa, Carlos J Blondel, Fernando A Amaya, Carlos A Santiviago
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Transfer of T6SSSPI-19 from Salmonella Gallinarum to Salmonella Typhimurium Lacking T6SSSPI-6 Complements its Colonization Defect in Mice.
Salmonella genus harbors five Type VI Secretion System (T6SS) gene clusters. The T6SS encoded in SPI-6 (T6SSSPI-6) contributes to Salmonella Typhimurium colonization of chickens and mice, while the T6SS encoded in SPI-19 (T6SSSPI-19) of Salmonella Gallinarum contributes to chicken colonization. Interestingly, the T6SSSPI-19 of Salmonella Gallinarum complemented the defect in chicken colonization of a Salmonella Typhimurium strain that lacks the T6SSSPI-6, suggesting that both T6SSs are interchangeable. Here we show that the transfer of Salmonella Gallinarum T6SSSPI-19 complemented the defect in mice colonization of a Salmonella Typhimurium ΔT6SSSPI-6 strain, indicating that both T6SSs are functionally redundant during host colonization.
期刊介绍：
Polish Journal of Microbiology (PJM) publishes original research articles describing various aspects of basic and applied microbiological research. We are especially interested in articles regarding
- basic biological properties of bacteria and archaea, viruses, and simple
- eukaryotic microorganisms
- genetics and molecular biology
- microbial ecology
- medical bacteriology and public health
- food microbiology
- industrial microbiology
- bacterial biotechnology
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