侧链的化学发生激活加速了食欲条件反应的消退。

IF 1.6 4区医学 Q3 BEHAVIORAL SCIENCES

Behavioral neuroscience Pub Date : 2023-04-01 DOI:10.1037/bne0000553

Dong-Hee Kim, Bo-Ryoung Choi, In-Beom Jin, Jin-Ah Jeon, Sang-Pil Park, Jung-Soo Han

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引用次数: 1

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Chemogenetic activation of lateral habenula accelerates the extinction of the appetitive conditioned responses.

A previous study reported lateral habenula (LHb) lesions decelerated appetitive extinction. Therefore, we examined whether LHb activation accelerated appetitive extinction. In this study, rats received appetitive Pavlovian conditioning, pairing a conditioned stimulus (CS, light) with an unconditioned stimulus (food pellets), followed by CS-alone presentations. Chemogenetic LHb activation accelerated the decline in conditioned food-cup responses during extinction. The present results and the reports of previous LHb lesion studies suggest that LHb mediates appetitive extinction. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

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来源期刊

Behavioral neuroscience 医学-行为科学

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Behavioral Neuroscience publishes original research articles as well as reviews in the broad field of the neural bases of behavior.